Results 131 to 140 of about 1,586,071 (235)

Structural disorder of plasmid-encoded proteins in Bacteria and Archaea

BMC Bioinformatics, 2018
Background In the last decade and a half it has been firmly established that a large number of proteins do not adopt a well-defined (ordered) structure under physiological conditions.
Nenad S. Mitić, Saša N. Malkov, Jovana J. Kovačević, Gordana M. Pavlović-Lažetić, Miloš V. Beljanski   +4 more
doaj   +1 more source

Quaternary structures of Streptococcus pneumoniae nucleoside diphosphate kinase: From hexamers to supramolecular assemblies

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The nucleoside diphosphate kinase (NDK) is a key enzyme that controls the balance of nucleotide pools in all living organisms. Beyond this fundamental role, NDKs exert pleiotropic effects in many cellular processes, including cell development, signal transduction, differentiation, tumor metastasis, and gene expression. The quaternary structure
Julie Kerboeuf, Paul Nouri, Frédéric Galisson, Laetitia Daury, Marie‐France Giraud, Olivier Lambert, Cédric Orelle, Lionel Ballut, Elise Kaplan, Jean‐Michel Jault, Cécile Gonzalez   +10 more
wiley   +1 more source

Antimicrobial Peptides, Polymorphic Toxins, and Self-Nonself Recognition Systems in Archaea: an Untapped Armory for Intermicrobial Conflicts

mBio, 2019
Numerous, diverse, highly variable defense and offense genetic systems are encoded in most bacterial genomes and are involved in various forms of conflict among competing microbes or their eukaryotic hosts.
Kira S. Makarova, Yuri I. Wolf, Svetlana Karamycheva, Dapeng Zhang, L. Aravind, Eugene V. Koonin   +5 more
doaj   +1 more source

Crystal Structure of an Archaeal Replication Protein A Homolog

The FASEB Journal, 2006
Single stranded DNA molecules that are generated during the course of replication are energetically unstable, and require engagement by single stranded DNA binding proteins to prevent re‐annealing. In bacteria, this process is mediated by a small polypeptide termed the single stranded DNA binding protein, while in eukaryotes, the replication protein A ...
Satish K. Nair, Brian Bae, Kent Lin, Isaac K. Cann   +3 more
openaire   +1 more source

Characterization of protein glycosylation in an Asgard archaeon

BBA Advances
Archaeal cells are typically enveloped by glycosylated S-layer proteins. Archaeal protein glycosylation provides valuable insights not only into their adaptation to their niches but also into their evolutionary trajectory.
Satoshi Nakagawa, Hiroyuki Imachi, Shigeru Shimamura, Saeko Yanaka, Hirokazu Yagi, Maho Yagi-Utsumi, Hiroyuki Sakai, Shingo Kato, Moriya Ohkuma, Koichi Kato, Ken Takai   +10 more
doaj   +1 more source

A protein chaperone can stabilize the intein‐containing precursor to indirectly promote protein splicing

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Intervening proteins (inteins) interrupt host protein sequences and are removed by a self‐mediated protein splicing reaction. Inteins are abundant in the microbial world and are often found within essential genes involved in DNA replication, recombination, and repair.
John S. Smetana, Christopher R. Powell, Noy Bagdadi, Tia M. Ariagno, Hazel Thomas, Joel Weinberger II, Eyal Gur, Christopher W. Lennon   +7 more
wiley   +1 more source

Archaeal NusA2 is the ancestor of ribosomal protein eS7 in eukaryotes

Structure
Structure 33(1), 149 - 159 (2025).
Phung, Duy Khanh, Pilotto, Simona, Matelska, Dorota, Blombach, Fabian, Pinotsis, Nikos, Hovan, Ladislav, Gervasio, Francesco Luigi, Werner, Finn   +7 more
openaire   +3 more sources

Structure and conformational dynamics of the Pseudomonas CbrA transceptor

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The CbrA protein is a central regulator of carbon metabolism, biofilm formation, and virulence in Pseudomonas species, but the molecular mechanisms by which CbrA links nutrient sensing to downstream signaling has remained unclear. CbrA is a rare “transceptor” that combines membrane transporter and histidine kinase domains into a single ...
Melanie A. Orlando, Tejas Shah, Matthew W. Faber, Samik Bose, Benjamin J. Orlando   +4 more
wiley   +1 more source

Navigating the archaeal frontier: insights and projections from bioinformatic pipelines

Frontiers in Microbiology
Archaea continues to be one of the least investigated domains of life, and in recent years, the advent of metagenomics has led to the discovery of many new lineages at the phylum level.
Val Karavaeva, Val Karavaeva, Filipa L. Sousa   +2 more
doaj   +1 more source

Supramolecular tholos-like architecture constituted by archaeal proteins without functional annotation. [PDF]

Sci Rep, 2020
Yagi-Utsumi M, Sikdar A, Song C, Park J, Inoue R, Watanabe H, Burton-Smith RN, Kozai T, Suzuki T, Kodama A, Ishii K, Yagi H, Satoh T, Uchiyama S, Uchihashi T, Joo K, Lee J, Sugiyama M, Murata K, Kato K.   +19 more
europepmc   +1 more source