Results 151 to 160 of about 6,523,049 (268)

Antimicrobial Peptides, Polymorphic Toxins, and Self-Nonself Recognition Systems in Archaea: an Untapped Armory for Intermicrobial Conflicts

mBio, 2019
Numerous, diverse, highly variable defense and offense genetic systems are encoded in most bacterial genomes and are involved in various forms of conflict among competing microbes or their eukaryotic hosts.
Kira S. Makarova, Yuri I. Wolf, Svetlana Karamycheva, Dapeng Zhang, L. Aravind, Eugene V. Koonin   +5 more
doaj   +1 more source

Structures of Saccharolobus solfataricus initiation complexes with leaderless mRNAs highlight archaeal features and eukaryotic proximity

Nature Communications
The archaeal ribosome is of the eukaryotic type. TACK and Asgard superphyla, the closest relatives of eukaryotes, have ribosomes containing eukaryotic ribosomal proteins not found in other archaea, eS25, eS26 and eS30.
Gabrielle Bourgeois, Pierre-Damien Coureux, Christine Lazennec-Schurdevin, Clément Madru, Thomas Gaillard, Magalie Duchateau, Julia Chamot-Rooke, Sophie Bourcier, Yves Mechulam, Emmanuelle Schmitt   +9 more
doaj   +1 more source

Interactions of Mucus Monosaccharides and the Epidermal Microbiome in Four Benthic Elasmobranchs

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Here we collected mucus and microbes from the skin of Elasmobranchs to identify interactions between mucus and the microbial community. We identified key microbial genes involved in the metabolism of mucus carbohydrates in Elasmobranchs. ABSTRACT Epidermal mucus is a complicated mixture of macromolecules which acts as the first line of defence for ...
Emma N. Kerr, Long Yu, Ryan D. Hesse, Chloe N. Roberts, Vincent Bulone, Lauren Meyer, Robert A. Edwards, Michael P. Doane, Elizabeth A. Dinsdale   +8 more
wiley   +1 more source

Navigating the archaeal frontier: insights and projections from bioinformatic pipelines

Frontiers in Microbiology
Archaea continues to be one of the least investigated domains of life, and in recent years, the advent of metagenomics has led to the discovery of many new lineages at the phylum level.
Val Karavaeva, Val Karavaeva, Filipa L. Sousa   +2 more
doaj   +1 more source

PRED-CLASS: cascading neural networks for generalized protein classification and genome-wide applications

, 2001
A cascading system of hierarchical, artificial neural networks (named PRED-CLASS) is presented for the generalized classification of proteins into four distinct classes-transmembrane, fibrous, globular, and mixed-from information solely encoded in their ...
Adams, Aloy, Apweiler, Bairoch, Brenner, Fariselli, Fariselli, Finkelstein, Fischer, Hamodrakas, Haykin, Hobohm, Jones, Koehl, Levitt, Minsky, Murzin, Murzin, Murzin, Möeller, Nielsen, Pasquier, Pasquier, Pasquier, Pedersen, Petersen, Rice, Rost, Rost, Rumelhart, Sanchez, Schulz, Stevens, Vlahou, Wallin   +34 more
core   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Human Intestinal Microbiota Composition Shapes Model Polyfluoroalkyl Substance Biotransformation

ChemBioChem, Volume 27, Issue 5, 13 March 2026.
Differences in the human gut microbiome impact the rate and pathway of biotransformation for 6:2 polyfluoroalkyl phosphate diester (diPAP), a model polyfluoroalkyl substance. Metabolic analysis is coupled to 16S RNA analysis to identify correlations between microbial taxa abundance and PAP transformation products not previously established from ...
Sierra T. Peskett, Daniel S. Grégoire, Amy A. Rand   +2 more
wiley   +1 more source

Characterization of protein glycosylation in an Asgard archaeon

BBA Advances
Archaeal cells are typically enveloped by glycosylated S-layer proteins. Archaeal protein glycosylation provides valuable insights not only into their adaptation to their niches but also into their evolutionary trajectory.
Satoshi Nakagawa, Hiroyuki Imachi, Shigeru Shimamura, Saeko Yanaka, Hirokazu Yagi, Maho Yagi-Utsumi, Hiroyuki Sakai, Shingo Kato, Moriya Ohkuma, Koichi Kato, Ken Takai   +10 more
doaj   +1 more source

Supramolecular tholos-like architecture constituted by archaeal proteins without functional annotation. [PDF]

Sci Rep, 2020
Yagi-Utsumi M, Sikdar A, Song C, Park J, Inoue R, Watanabe H, Burton-Smith RN, Kozai T, Suzuki T, Kodama A, Ishii K, Yagi H, Satoh T, Uchiyama S, Uchihashi T, Joo K, Lee J, Sugiyama M, Murata K, Kato K.   +19 more
europepmc   +1 more source

A Quantitative Approach to Investigating the Hypothesis of Prokaryotic Intron Loss [PDF]

, 2011
Using a novel method, we show that ordered triplets of motifs usually associated with spliceosomal intron recognition are underrepresented in the protein coding sequence of complete Thermotogae, archaeal and bacterial genomes.
Robert M. Sinclair
core   +1 more source