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Exploring the archaeal origin of eukaryotic protein machineries
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Biochemical Society Transactions, 2011
PCNA (proliferating-cell nuclear antigen) is a ring-shaped protein that encircles duplex DNA and plays an essential role in many DNA metabolic processes. The PCNA protein interacts with a large number of cellular factors and modulates their enzymatic activities.
Miao, Pan, Lori M, Kelman, Zvi, Kelman
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PCNA (proliferating-cell nuclear antigen) is a ring-shaped protein that encircles duplex DNA and plays an essential role in many DNA metabolic processes. The PCNA protein interacts with a large number of cellular factors and modulates their enzymatic activities.
Miao, Pan, Lori M, Kelman, Zvi, Kelman
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Journal of Molecular Biology, 2011
Protein synthesis occurs in macromolecular particles called ribosomes. All ribosomes are composed of RNA and proteins. While the protein composition of bacterial and eukaryotic ribosomes has been well-characterized, a systematic analysis of archaeal ribosomes has been lacking.
Viter, Márquez +10 more
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Protein synthesis occurs in macromolecular particles called ribosomes. All ribosomes are composed of RNA and proteins. While the protein composition of bacterial and eukaryotic ribosomes has been well-characterized, a systematic analysis of archaeal ribosomes has been lacking.
Viter, Márquez +10 more
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Structural Dynamics of Archaeal Small Heat Shock Proteins
Journal of Molecular Biology, 2008Small heat shock proteins (sHsps) are a widespread and diverse class of molecular chaperones. In vivo, sHsps contribute to thermotolerance. Recent evidence suggests that their function in the cellular chaperone network is to maintain protein homeostasis by complexing a variety of non-native proteins.
Martin, Haslbeck +4 more
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Functions of Archaeal Nucleoid Proteins: Archaeal Silencers are Still Missing
2019It is well known that horizontally transferred genes (HTGs) contribute to the adaptation of archaea to their living environment. Archaea have acquired HTGs not only from other archaea but also from bacteria. HTGs should be integrated into the host archaeal transcriptional networks to become functional.
Hugo Maruyama +3 more
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The protein sequence of an archaeal catalase-peroxidase
Biochimie, 1998The gene encoding a catalase-peroxidase of archaeal origin, the halophilic catalase-peroxidase from Haloarcula marismortui, was sequenced. The primary structure proposed was confirmed by Edman degradation and mass spectrometry analyses of proteolytic fragments of the purified protein.
V, Cannac-Caffrey +5 more
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Protein–protein interactions in the archaeal core replisome
Biochemical Society Transactions, 2011Most of the core components of the archaeal chromosomal DNA replication apparatus share significant protein sequence similarity with eukaryotic replication factors, making the Archaea an excellent model system for understanding the biology of chromosome replication in eukaryotes.
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2012
The initiation of DNA replication in most archaeal genomes is mediated by proteins related to eukaryotic Orc1 and Cdc6. Archaeal replication origins have been mapped and their interactions with Orc1/Cdc6 proteins have been characterized at the biochemical level. Structural and biophysical studies have revealed the basic rules of sequence recognition by
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The initiation of DNA replication in most archaeal genomes is mediated by proteins related to eukaryotic Orc1 and Cdc6. Archaeal replication origins have been mapped and their interactions with Orc1/Cdc6 proteins have been characterized at the biochemical level. Structural and biophysical studies have revealed the basic rules of sequence recognition by
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Facing extremes: archaeal surface-layer (glyco)proteins
Microbiology, 2003Archaea are best known in their capacities as extremophiles, i.e. micro-organisms able to thrive in some of the most drastic environments on Earth. The protein-based surface layer that envelopes many archaeal strains must thus correctly assemble and maintain its structural integrity in the face of the physical challenges associated with, for instance ...
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