Results 51 to 60 of about 28,641 (215)

A New Era for Using Natural Pigments: The Case of the C50 Carotenoid Called Bacterioruberin

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Haloarchaea are extremophilic microorganisms belonging to the Archaea domain that require high salt concentrations to live, thus inhabiting ecosystems like salty ponds, salty marshes, or extremely salty lagoons. They are more abundant and widely distributed worldwide than initially expected.
Micaela Giani, Elena Valdés, José María Miralles‐Robledillo, Guillermo Martínez, Carmen Pire, Rosa María Martínez‐Espinosa   +5 more
wiley   +1 more source

Protein phosphorylation and its role in archaeal signal transduction [PDF]

FEMS Microbiology Reviews, 2016
Reversible protein phosphorylation is the main mechanism of signal transduction that enables cells to rapidly respond to environmental changes by controlling the functional properties of proteins in response to external stimuli. However, whereas signal transduction is well studied in Eukaryotes and Bacteria, the knowledge in Archaea is still rather ...
Esser, Dominik, Hoffmann, Lena, Pham, Trong Khoa, Bräsen, Christopher, Qiu, Wen, Wright, Phillip C., Albers, Sonja Verena, Siebers, Bettina   +7 more
openaire   +5 more sources

Metagenomic mining reveals novel Cas12 subtypes and their evolutionary diversification

iMetaOmics, EarlyView.
We identified 4112 Cas12 Proteins and 6 new Cas12 subtypes, revealed their significant diversity in N‐terminal regions, repeat sequences, and sequences motifs. We developed an AI‐driven algorithm, Cas12fam, which allows precise annotation of 18 distinct domains in Cas12 proteins.
Meixia Yu, Zilong Zhao, Peiyang Li, Yunpeng Teng, Feng Xu, Zhimeng Li, Zhijia Yang, Hainan Zhao, Huanbin Zhou, Lanqin Xia, Jinsheng Lai, Beibei Xin   +11 more
wiley   +1 more source

A YidC-like Protein in the Archaeal Plasma Membrane [PDF]

Structure, 2015
Cells possess specialized machinery to direct the insertion of membrane proteins into the lipid bilayer. In bacteria, the essential protein YidC inserts certain proteins into the plasma membrane, and eukaryotic orthologs are present in the mitochondrial inner membrane and the chloroplast thylakoid membrane.
Borowska, Marta T., Dominik, Pawel K., Anghel, S. Andrei, Kossiakoff, Anthony A., Keenan, Robert J.   +4 more
openaire   +2 more sources

Regulatory sequence-based discovery of anti-defense genes in archaeal viruses

Nature Communications
In silico identification of viral anti-CRISPR proteins (Acrs) has relied largely on the guilt-by-association method using known Acrs or anti-CRISPR associated proteins (Acas) as the bait.
Yuvaraj Bhoobalan-Chitty, Shuanshuan Xu, Laura Martinez-Alvarez, Svetlana Karamycheva, Kira S. Makarova, Eugene V. Koonin, Xu Peng   +6 more
doaj   +1 more source

Ribosomal RNA operon copy number: A trait‐informed framework to close the microbial cultivation gap

iMetaOmics, EarlyView.
The vast majority of microbes remain uncultured, constraining functional validation and limiting microbiome‐based applications. We show that ribosomal RNA operon (rrn) copy number—a stable, phylogenetically conserved genomic trait—is strongly correlated with cultivation outcomes across ecosystems.
Yuxiao Huang, Qingliu Wu, Chang Liu, Pugang Yu, Hao Li, Shengyue Tang, Fusuo Zhang, Shuangjiang Liu, Bin Ni   +8 more
wiley   +1 more source

Ubiquitin-like small archaeal modifier proteins (SAMPs) in Haloferax volcanii [PDF]

Nature, 2010
Archaea, one of three major evolutionary lineages of life, encode proteasomes highly related to those of eukaryotes. In contrast, archaeal ubiquitin-like proteins are less conserved and not known to function in protein conjugation. This has complicated our understanding of the origins of ubiquitination and its connection to proteasomes.
Humbard, Matthew A., Miranda, Hugo V., Lim, Jae-Min, Krause, David J., Pritz, Jonathan R., Zhou, Guangyin, Chen, Sixue, Wells, Lance, Maupin-Furlow, Julie A.   +8 more
openaire   +2 more sources

DNA interference and beyond: structure and functions of prokaryotic Argonaute proteins

Nature Communications, 2018
In this review, Aravin and colleagues examine bacterial and archaeal Argonaute proteins, discuss their diverse architectures and their possible roles in host defense, proposing additional functions for Argonaute proteins in prokaryotic cells.
Lidiya Lisitskaya, Alexei A. Aravin, Andrey Kulbachinskiy   +2 more
doaj   +1 more source

Diversity, transfer potential, and transcriptional activity of virus‐carried antibiotic resistance genes in global estuaries

iMetaOmics, EarlyView.
Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo, Xiyang Dong, Jia‑Ling Li, Ji‐Cheng Yao, Ziqi Peng, Qi Li, Zi‐Wen Yang, Yang Yuan, Wen‑Jun Li, Pandeng Wang   +9 more
wiley   +1 more source

Characterization of a small tRNA‐binding protein that interacts with the archaeal proteasome complex [PDF]

, 2022
Gaëlle Hogrel, Laura Marino‐Puertas, Sébastien Laurent, Ziad Ibrahim, Jacques Covès, Éric Girard, Frank Gabel, Daphna Fenel, Marie‐Claire Daugeron, Béatrice Clouet-d’Orval, Tamara Basta, Didier Flament, Bruno Franzetti   +12 more
openalex   +1 more source