Results 61 to 70 of about 9,655 (192)
Archaeal viruses at the cell envelope: entry and egress
Frontiers in Microbiology, 2015 The cell envelope represents the main defense of host that viruses encounter on their way from one cell to another. The cytoplasmic membrane in general is a physical barrier that needs to be crossed both upon viral entry and exit. Therefore, viruses from
Emmanuelle R.J. Quemin +1 more
doaj +1 more source
In Vivo Assembly of an Archaeal Virus Studied with Whole-Cell Electron Cryotomography [PDF]
Structure, 2010 We applied whole-cell electron cryotomography to the archaeon Sulfolobus infected by Sulfolobus turreted icosahedral virus (STIV), which belongs to the PRD1-Adeno lineage of dsDNA viruses. STIV infection induced the formation of pyramid-like protrusions with sharply defined facets on the cell surface.
Fu, Chi-yu +8 more
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Global analysis of viral infection in an archaeal model system
Frontiers in Microbiology, 2012 The origin and evolutionary relationship of viruses is poorly understood. This makes archaeal virus-host of particular interest because the hosts generally root near the base of phylogenetic trees, while some of the viruses have clear structural ...
Walid S. Maaty +9 more
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Monoallelic POLR3A Variants Cause Early‐Onset Peripheral Neuropathy
Annals of Neurology, EarlyView.Objective Biallelic variants in genes encoding the RNA polymerase III complex (Pol III) cause a spectrum of neurological disorders primarily affecting the central nervous system. Monoallelic variants have been reported in the POLR3B subunit only, associated with neurodevelopmental disorder, epilepsy, and peripheral neuropathy.
Luiza L. P. Ramos +46 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik +3 more
wiley +1 more source
Viruses, 2023 ABSTRACT Lytic viruses can be prevalent in deep groundwater, yet their spatial and temporal distribution in such an ecosystem remains unexplored. Here, we tackle this gap of knowledge by studying viral infections in individual, archaea-dominated biofilm flocks sampled from deep anoxic groundwater over a period of ...
Victoria Turzynski +8 more
openaire +5 more sources
Eukaryotic-Like Virus Budding in
mBio, 2016 Similar to many eukaryotic viruses (and unlike bacteriophages), viruses infecting archaea are often encased in lipid-containing envelopes. However, the mechanisms of their morphogenesis and egress remain unexplored.
Emmanuelle R. J. Quemin +5 more
doaj +1 more source
Genome editing in archaeal viruses and endogenous viral protein purification
STAR Protocols, 2021 Summary: Archaea-infecting viruses are morphologically and genomically among the most diverse entities. Unfortunately, they are also fairly understudied due to a lack of efficient genetic tools.
Lauge Alfastsen +2 more
doaj +1 more source
System analysis of synonymous codon usage biases in archaeal virus genomes. [PDF]
J Theor Biol, 2014 Recent studies of geothermally heated aquatic ecosystems have found widely divergent viruses with unusual morphotypes. Archaeal viruses isolated from these hot habitats usually have double-stranded DNA genomes, linear or circular, and can infect members of the Archaea domain.
Li S, Yang J.
europepmc +3 more sources
Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance
Interdisciplinary Medicine, EarlyView.This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang +14 more
wiley +1 more source