Results 81 to 90 of about 1,138,050 (191)

Differentiation and Structure in Sulfolobus islandicus Rod-Shaped Virus Populations

Viruses, 2017
In the past decade, molecular surveys of viral diversity have revealed that viruses are the most diverse and abundant biological entities on Earth. In culture, however, most viral isolates that infect microbes are represented by a few variants isolated ...
Maria A. Bautista, Jesse A. Black, Nicholas D. Youngblut, Rachel J. Whitaker   +3 more
doaj   +1 more source

Genome editing in archaeal viruses and endogenous viral protein purification

STAR Protocols, 2021
Summary: Archaea-infecting viruses are morphologically and genomically among the most diverse entities. Unfortunately, they are also fairly understudied due to a lack of efficient genetic tools.
Lauge Alfastsen, Xu Peng, Yuvaraj Bhoobalan-Chitty   +2 more
doaj   +1 more source

Seasonal Dynamics of Community and Function of Gut Microbiome in Taihangshan Macaque (Macaca mulatta tcheliensis): Inferred From Metagenomic Data

Integrative Zoology, EarlyView.
A total of 435 non‐redundant metagenome‐assembled genomes (MAGs) were obtained from fecal samples of Taihangshan macaque across all four seasons. The alpha diversity of the gut microbiome in spring and winter was significantly higher than in summer and autumn. Furthermore, marked differences were detected in functional pathways and carbohydrate enzymes
Yanyan Zhou, Qi Shao, Chunbo Liu, Jundong Tian, Xiaowen Guan, Xi Zhang, Jiqi Lu   +6 more
wiley   +1 more source

Game-Theoretical Modeling of Interviral Conflicts Mediated by Mini-CRISPR Arrays

Frontiers in Microbiology, 2020
All cellular organisms coevolve with multiple viruses, so that both virus-host and intervirus conflicts are major factors of evolution. Accordingly, hosts evolve multiple, elaborate defense systems and viruses respond by evolving means of antidefense ...
Jaime Iranzo, Jaime Iranzo, Jaime Iranzo, Guilhem Faure, Yuri I. Wolf, Eugene V. Koonin   +5 more
doaj   +1 more source

Testing for Bacteria and Fungi in Cells and Ancillary Reagents—Probe‐Based Quantitative PCR Assays

Cell Proliferation, EarlyView.
This document specifies the technical elements for bacteria and fungi detection by PCR assay which enables rapid, broad‐spectrum detection of bacteria and fungi with high sensitivity. Qualitative judgement is based on LOD. Key detection points include efficient nucleic acid extraction, broad‐spectrum primer‐probe design, high amplification efficiency ...
Jiani Cao, Ranran Xu, Boqiang Fu, Jie Hao, Lei Wang, Aijin Ma, Qiang Wei, Hongling Zhao, Chunming Rao, Qiyuan Li, Tao Na, Shijun Hu, Lihua Zhou, Weiqi Zhang, Qubo Chen, Siming Sun, Zengshu Liu, Shuaishuai Niu, Tingting Zhang, Yuanyuan Zhang, Yidi Gan, Shuyan Wang, Glyn N. Stacey, Jun Wei, Tongbiao Zhao, Yu Alex Zhang   +25 more
wiley   +1 more source

An archaeal chronic virus escapes the immunity of prokaryotic Argonaute

Nucleic Acids Research
Abstract Bacteria and archaea use diverse defense systems to defeat their viruses, and in turn, viruses develop anti-defense strategies to overcome the host immunity. Catalytically inactive prokaryotic Argonaute proteins constitute a family of defense systems that kill infected cells to halt viral propagation, whereas how viruses escape ...
Yu Chen, Yanqiu Liu, Keyi Tan, Ke Yang, Zhifeng Zeng, Yu Guo, Piaoran Zhang, Wenyuan Han   +7 more
openaire   +2 more sources

Discovery and characterization of complete genomes of 38 head-tailed proviruses in four predominant phyla of archaea

Microbiology Spectrum
Archaea play a significant role in natural ecosystems and the human body. Archaeal viruses exert a considerable influence on the structure and composition of archaeal communities and their associated ecological environments.
Tianqi Xu, Yimin Ni, Hailing Li, Shuang Wu, Shuling Yan, Lanming Chen, Yongxin Yu, Yongjie Wang   +7 more
doaj   +1 more source

HCIV-1 and Other Tailless Icosahedral Internal Membrane-Containing Viruses of the Family Sphaerolipoviridae

Viruses, 2017
Members of the virus family Sphaerolipoviridae include both archaeal viruses and bacteriophages that possess a tailless icosahedral capsid with an internal membrane.
Tatiana A. Demina, Maija K. Pietilä, Julija Svirskaitė, Janne J. Ravantti, Nina S. Atanasova, Dennis H. Bamford, Hanna M. Oksanen   +6 more
doaj   +1 more source

Eukaryogenesis: The Rise of an Emergent Superorganism

Frontiers in Microbiology, 2022
Although it is widely taught that all modern life descended via modification from a last universal common ancestor (LUCA), this dominant paradigm is yet to provide a generally accepted explanation for the chasm in design between prokaryotic and ...
Philip J. L. Bell
doaj   +1 more source

Automated reconstruction of reproducible protein databases with RepDBmaker

Protein Science, Volume 35, Issue 11, November 2026.
Abstract RepDBmaker is a reproducible Snakemake pipeline designed for the automated construction of large‐scale protein sequence databases. It enables the seamless downloading of sequences from different public databases and the integration of user‐specified proteomes.
Giacomo Mutti, Toni Gabaldón
wiley   +1 more source