Responses of hyperthermophilic crenarchaea to UV irradiation [PDF]
This work was supported by a dedicated functional genomics grant from the Swedish Research Council and the Swedish Graduate Research School in Genomics and Bioinformatics to RB, and by grants from the Wellcome Trust and BBSRC to MFW.Background: DNA ...
Lundgren, Magnus, +14 more
core +1 more source
A Glimpse of the genomic diversity of haloarchaeal tailed viruses
Tailed viruses are the most common isolates infecting prokaryotic hosts residing hypersaline environments. Archaeal tailed viruses represent only a small portion of all characterized tailed viruses of prokaryotes.
Ana eSencilo +3 more
doaj +1 more source
Mechanisms That Govern Recombinase Fidelity Control During Eukaryotic Homologous Recombination
The rate of recombinase filament formation controls the fidelity of the homologous recombination reaction by either restricting the length of strand pairing for high‐fidelity repair or increasing the length of strand pairing for more complex outcomes.
Ilayda Korkmaz, J. Brooks Crickard
wiley +1 more source
Deep Mutational Scanning for the Study and Engineering of Protein Assemblies
This review explores how deep mutational scanning (DMS) can be used to improve understanding and accelerate engineering of protein assemblies, from natural fibers to engineered nanocages. We discuss various types of protein assemblies and their characterization, provide an introduction to the DMS technique, and then highlight examples in which DMS has ...
Jenna B. Wolfanger +2 more
wiley +1 more source
Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail [PDF]
While archaeal viruses show a stunning diversity of morphologies, many bear a notable resemblance to tailed bacterial phages. This raises fundamental questions: Do all tailed viruses share a common origin and do they infect their hosts in similar ways ...
Quax, Tessa E F; id_orcid +17 more
core +1 more source
Assembly of complex viruses exemplified by a halophilic euryarchaeal virus
Here, the authors present the cryo-EM structure of the archaeal virus SH1 at 3.8 Å resolution and show how the major capsid proteins assemble into hetero-hexamers, providing insights into the assembly process of this and related PRD1-adeno lineage ...
Luigi De Colibus +9 more
doaj +1 more source
A new example of viral intein in Mimivirus
Background Inteins are "protein introns" that remove themselves from their host proteins through an autocatalytic protein-splicing. After their discovery, inteins have been quickly identified in all domains of life, but only once to date in the genome of
Claverie Jean-Michel +2 more
doaj +1 more source
Characterisation of XPD from Sulfolobus acidocaldarius : an iron-sulphur cluster containing DNA repair helicase [PDF]
DNA is constantly damaged by a variety of exogenous and endogenous sources. To maintain the integrity of the genome, different DNA repair mechanisms have evolved, which deal with different kinds of DNA damage.
Rudolf, Jana
core +2 more sources
Sequence analysis of an Archaeal virus isolated from a hypersaline lake in Inner Mongolia, China
Background We are profoundly ignorant about the diversity of viruses that infect the domain Archaea. Less than 100 have been identified and described and very few of these have had their genomic sequences determined.
Ma Yanhe +7 more
doaj +1 more source
Dimer-dimer stacking interactions are important for nucleic acid binding by the archaeal chromatin protein Alba [PDF]
Archaea use a variety of small basic proteins to package their DNA. One of the most widespread and highly conserved is the Alba (Sso10b) protein. Alba interacts with both DNA and RNA in vitro, and we show in the present study that it binds more tightly ...
Petrovic-Stojanovska, Biljana +4 more
core +1 more source

