Results 91 to 100 of about 1,138,050 (191)

Long Non‐Coding RNAs: Key Regulators of Economic Traits in Livestock From Mechanisms to Breeding Applications

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Long non‐coding RNAs (lncRNAs) act as key regulators of economically important traits in livestock through diverse mechanisms including ceRNA networks, epigenetic regulation (X‐inactivation and imprinting) and liquid–liquid phase separation (LLPS).
Keyvan Khani, Mohammad Taher Harkinezhad, Rahimeh Sepehri   +2 more
wiley   +1 more source

Impact Crater Hydrothermal Systems Support Rapid Microbial Enrichment and Diverse Metabolic Potential

Geobiology, Volume 24, Issue 6, November/December 2026.
ABSTRACT Impact crater hydrothermal systems, formed after asteroid and comet impacts, have been proposed as promising habitats for life on early Earth and as key targets in the search for life on planetary bodies such as Mars, since they provide liquid water and active geochemical turnover.
Sabrina M. C. Hardy, Emily J. Aguilar‐Pine, Sean Gulick, Alaa Ahmad, Brett J. Baker, Nathalie Scott, Georgina Aitolo, Naomi Felton, Charles S. Cockell   +8 more
wiley   +1 more source

ORF157 from the Archaeal VirusAcidianusFilamentous Virus 1 Defines a New Class of Nuclease [PDF]

Journal of Virology, 2010
ABSTRACTAcidianusfilamentous virus 1 (AFV1) (Lipothrixviridae) is an enveloped filamentous virus that was characterized from a crenarchaeal host. It infectsAcidianusspecies that thrive in the acidic hot springs (>85°C and pH <3) of Yellowstone National Park, WY. The AFV1 20.8-kb, linear, double-stranded DNA genome encodes 40 putative open reading
Adeline, Goulet, Mery, Pina, Peter, Redder, David, Prangishvili, Laura, Vera, Julie, Lichière, Nicolas, Leulliot, Herman, van Tilbeurgh, Miguel, Ortiz-Lombardia, Valérie, Campanacci, Christian, Cambillau   +10 more
openaire   +2 more sources

Structural basis of RNA polymerase inhibition by viral and host factors

Nature Communications, 2021
Understanding the structural basis for the inhibition of archaeal eukaryotic-like RNA polymerases (RNAPs) during virus infection is of interest for drug design.
Simona Pilotto, Thomas Fouqueau, Natalya Lukoyanova, Carol Sheppard, Soizick Lucas-Staat, Luis Miguel Díaz-Santín, Dorota Matelska, David Prangishvili, Alan C. M. Cheung, Finn Werner   +9 more
doaj   +1 more source

Shotgun Metagenomic Analysis Reveals Taxonomic and Functional Transitions in the Salivary Microbiome During Periodontal Disease Progression

Journal of Clinical Periodontology, Volume 53, Issue 11, Page 1650-1662, November 2026.
ABSTRACT Aim To characterise multi‐kingdom salivary microbiome profiles across clinically defined periodontal states and identify stage‐specific taxonomic and functional alterations using shotgun metagenomic sequencing. Materials and Methods In this cross‐sectional study, 204 adults (mean age 40.3 ± 7.6 years) from the SECRETO study (NCT01934725 ...
Muhammed Manzoor, Jaakko Leskelä, Eija Könönen, Leo Lahti, Jukka Putaala, Pirkko J. Pussinen, Susanna Paju   +6 more
wiley   +1 more source

Viruses of archaea: Structural, functional, environmental and evolutionary genomics

, 2018
International audienceViruses of archaea represent one of the most enigmatic parts of the virosphere. Most of the characterized archaeal viruses infect extremophilic hosts and display remarkable diversity of virion morphotypes, many of which have never ...
Iranzo, Jaime, Mart Krupovic, David Prangishvili, Koonin, Eugene, Krupovic, Mart, Prangishvili, David, Jaime Iranzo, Virginija Cvirkaite-Krupovic, Cvirkaite-Krupovic, Virginija, Eugene V. Koonin   +9 more
core   +1 more source

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This review summarizes the pathogenic role of mitochondria in diseases and highlights mitochondrial transfer and transplantation as emerging therapeutic strategies. It systematically discusses how nanomaterials are engineered to facilitate these processes, and critically examines the current challenges and future perspectives for their clinical ...
Yuanyuan Su, Zhiyan Gong, Jiao Mu, Lili Huang, Pengfei Yang, Chenli Zhang, Lingshan Zhao, Liling Yang, Jun Deng, Xiaohui Liao   +9 more
wiley   +1 more source

Taming Mre11–Rad50 at Telomeres: Convergent Strategies for Chromosome‐End Protection Across Evolution

BioEssays, Volume 48, Issue 10, October 2026.
All telomeres must be protected from DNA repair enzymes. This review explores how, from bacteriophages to mammals, unrelated telomere proteins have converged on the same recurring strategies: inhibiting the Mre11–Rad50 nuclease directly or physically shielding DNA ends. ABSTRACT Telomere biology is often framed as a uniquely eukaryotic problem, yet the
Florian Roisné‐Hamelin, Stephan Gruber   +1 more
wiley   +1 more source

Influences of soil properties on archaeal diversity and distribution in the McMurdo Dry Valleys, Antarctica [PDF]

, 2011
The Antarctic Dry Valleys are characterized by extremely low temperatures, arid conditions, high salinity and virtual absence of plants. Therefore, food webs of these microbially dominated soils are among the simplest on earth making these mineral soils ...
Richter, Ingrid
core  

System analysis of synonymous codon usage biases in archaeal virus genomes

Journal of Theoretical Biology, 2014
Recent studies of geothermally heated aquatic ecosystems have found widely divergent viruses with unusual morphotypes. Archaeal viruses isolated from these hot habitats usually have double-stranded DNA genomes, linear or circular, and can infect members of the Archaea domain.
Li, Sen, Yang, Jie
openaire   +2 more sources