Results 121 to 130 of about 76,245 (285)
In search of a circular supply chain archetype – a content-analysis-based literature review
, 2018 L. Batista +3 more
semanticscholar +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Using focus groups data to finalize the Archetypes
, 2019 Marco Antonio Ortiz Sanchez +2 more
openalex +2 more sources
4 Archetype Reasons for Editorial Rejection [PDF]
, 2020 Stacey Chin, Steven W. Cranford
openalex +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
ELEMENTS OF THE MUSICAL DISCOURSE IN “FUM (SMOKE)” BY DOINA ROTARU
Studia Universitatis Babeş-Bolyai. Musica, 2012 The present study is an analysis of the work entitled Fum (Smoke), for clarinet solo, written by the Romanian composer Doina Rotaru in 1996 and dedicated to the clarinetist Emil Vişenescu.
Şerban MARCU
doaj
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source