Results 101 to 110 of about 37,709 (292)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
PECULIARITIES OF ARCHETYPES’ REPRODUCTION IN THE TRANSLATION OF AN ARTISTIC WORK
Іноземна філологіяThe article examines the peculiarities of reproduction of archetypes in the translation of an artistic work. The interpretation of the concept of ‘archetype’, its classifi cations and levels of its mental representation in the text are studied herein ...
Mariia Kravtsova
doaj +1 more source
Using archetype thinking to upscale land-based sustainability solutions
, 2019 There is broad agreement that solutions to land-based sustainability challenges need to be contextualised to specific conditions and actors. For example, promising sustainable land management practices (SLM) might look quite different in tropical or dry ...
Schneider, Flurina
core
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
ARQThe Seasonal Forestry Archetype proposes an alternative, community-oriented approach to forestry in Ucayali, integrating wood processing plants with local communities.
Maryhori Quispe Castillo
doaj +1 more source
Nine archetype set for the high MI county set.
Presented as color-coded counties in map of Montana. The first archetype is not included, as it captures the “no disease” state, and acts to “turn-off” the disease in each county.
Emily Stone (5804144) +2 more
core +1 more source
Face recognition via archetype hull ranking
, 2013 The archetype hull model is playing an important role in large-scale data analytics and mining, but rarely applied to vision problems. In this paper, we migrate such a geometric model to address face recognition and verification together through ...
Deli Zhao +3 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source