Results 121 to 130 of about 28,177 (302)

Example of an archetype expressed in ADL.

open access: yes, 2016
The archetype defines a generic sports racket.
Luca Lianas (3392201)   +3 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The Mother Archetype in Advertising

open access: yes, 2014
Tato bakalářská práce se zabývá problematikou projevů a užití archetypu matky v reklamě. Teoretická část objasňuje pojem archetyp, archetyp matky, reklama, gender a genderová stereotypizace.
Karolová, Martina
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Determinants of Archetype BK Polyomavirus Replication. [PDF]

open access: yes, 2013
BK polyomavirus (BKPyV) is a widespread, small double-stranded DNA virus that is an emerging pathogen in immunocompromised individuals. Following an initial asymptomatic infection, it establishes persistence in the urinary tract of its human host.
Broekema, Nicole Marie
core  

A Universal BRDF Archetype Database for Normalizing Directional Reflectance to Nadir BRDF Adjusted Reflectance

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Surface reflectance varies with changes in solar and viewing angles, exhibiting distinct anisotropic reflectance characteristics, which can be characterized using the bidirectional reflectance distribution function (BRDF).
Qianrui Xi   +7 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

A Stepmother Archetype

open access: yes, 1994
The Archetype of the Stepmother is a thesis which examines the role of the stepmother from an historical perspective stepmother in fairy tales and myth, the stepmother in psychological literature, stepmothers as they see themselves and images of the ...
Fink, Georgia Jackman
core  

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