Results 141 to 150 of about 76,245 (285)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Archetypal Analysis Reveals Consistent Visual Field Patterns for Stimulus Size III and Size Modulation Perimetry in Glaucoma. [PDF]

Transl Vis Sci Technol
Szanto D, Linton E, Wall M.
europepmc   +1 more source

72P Predictive value of spatially-derived archetypes and tertiary lymphoid structure signature in the NeoTRIP trial

Matteo Dugo, David Venet, Chiun‐Sheng Huang, Xiaoyang Wang, Daniel Egle, Maurizio Callari, Marcela Carausu, B. Bermejo, C. Zamagni, Marie‐Paule Thill, A. Antón Torres, Sofía Russo, Eva Ciruelos, Balázs Győrffy, Françoise Rothé, G. Viale, Luca Gianni, Giampaolo Bianchini, C. Sotiriou   +18 more
openalex   +2 more sources

Archetypes and ancestors [PDF]

, 1994
Colin Patterson
openalex   +1 more source

The Neotethyan Sanandaj‐Sirjan zone of Iran as an archetype for passive margin‐arc transitions

, 2016
J. Hassanzadeh, B. Wernicke
semanticscholar   +1 more source

Redox tuning the Weakley-type polyoxometalate archetype for the oxygen evolution reaction

Nature Catalysis, 2018
Mercè Martin-Sabi, Joaquín Soriano-López, Ross S. Winter, Jiajia Chen, Laia Vilà‐Nadal, D. Long, J. Galán‐Mascarós, L. Cronin   +7 more
semanticscholar   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Five archetypes of small-scale fisheries reveal a continuum of production strategies to guide governance and policymaking. [PDF]

Nat Food
Aguión A, Basurto X, Funge-Smith S, Gorelli G, Iversen E, Mancha-Cisneros MDM, Gutierrez NL.   +6 more
europepmc   +1 more source

SNOMED CT module-driven clinical archetype management

, 2013
J.L. Allones, M. Taboada, D. Martínez, R. Lozano, María‐Jesús Sobrido   +4 more
openalex   +2 more sources

Key role for inhibins in effective T cell activation, migration and Th17 differentiation

FEBS Open Bio, EarlyView.
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco, Roxana Olguín‐Alor, Lizbeth Bolaños‐Castro, Alexandra Morales‐Cruz, Marisol De La Fuente‐Granada, Gloria Soldevila   +5 more
wiley   +1 more source