Results 91 to 100 of about 97,500 (274)

The governance of federated learning: a decision framework for organisational archetypes

open access: yesData & Policy
Federated learning (FL) is a machine learning technique that distributes model training to multiple clients while allowing clients to keep their data local. Although the technique allows one to break free from data silos keeping data local, to coordinate
Tom Barbereau   +2 more
doaj   +1 more source

The Palimpsest Girl in Ice by Anna Kavan

open access: yesMiranda: Revue Pluridisciplinaire du Monde Anglophone, 2016
Anna Kavan’s last novel Ice (1967) stages the obsessive quest of a man looking for an albino woman he can never reach. He constantly sees then loses this female character who is simply called “the girl”. This article analyses the place of her body in the
Céline Magot
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

THE PLOT OF THE FOOL’S INITIATION IN THE NOVEL BY L. N. TOLSTOY “THE COSSACKS”

open access: yesФилологический класс, 2019
The functions of the initiation plot in the novel by L. N. Tolstoy “The Cossacks” are considered in the artistic paradigm of the archetype of the Fool – one of the key figures of a folk tale whose traits are clearly readable in the structure of the ...
doaj   +1 more source

The World War II Patriotic Mother [PDF]

open access: yes, 2010
The archetypal good mother and the archetypal patriotic mother are important symbols in American culture. Both are rooted in maternal work but are separated by two conflicting assumptions. The good mother nurtures her children and protects them from harm,
Garner, Ana C., Slattery, Karen L.
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

THE CHARACTER OF REYNARD THE FOX IN THE CHILDREN’S LITERATURE OF FRANCE, GERMANY AND LUXEMBURG (SECOND HALF OF THE 20TH – BEGINNING OF THE 21ST CENTURIES)

open access: yesФилологический класс, 2019
The article focuses on the variants of representation and author’s interpretation of the title character of the medieval fables “Reynard the Fox” in the children’s literature of three countries.
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Archetypes of community-based pond aquaculture in Indonesia: applying the social-ecological systems framework to examine sustainability tradeoffs

open access: yesEnvironmental Research Letters
We analyze archetypes of farmer groups conducting pond aquaculture across the province of Nusa Tenggara Barat, Indonesia using Ostrom’s social-ecological systems framework.
Ben Nagel   +2 more
doaj   +1 more source

A Generative Model of Group Conversation

open access: yes, 2017
Conversations with non-player characters (NPCs) in games are typically confined to dialogue between a human player and a virtual agent, where the conversation is initiated and controlled by the player.
Martens, Chris, Morrison, Hannah
core   +1 more source

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