Results 51 to 60 of about 97,500 (274)
Frontiers in Systems BiologyOne of the main challenges in cancer treatment is the selection of treatment resistant clones which leads to the emergence of resistance to previously efficacious therapies.
Jonatan Blais, Julie Jeukens
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
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RESTAURANTE UNIVERSITÁRIO DA UFPE: UMA ABORDAGEM SISTÊMICA
Revista Gestão Universitária na América Latina, 2018 This study aims to analyze a problem situation of the university restaurant of the Federal University of Pernambuco regarding the limited capacity of the service in the light of systems theory.
Carla Ionara Xavier da Silveira Cardoso +4 more
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Disability Studies Quarterly, 2022 This article analyzes the depictions disability embodies in the fantasy film series Star Wars. Fantasy as a genre is able to re-present our past and present values through visionary forms and can act as a mirror to the society that creates the image ...
Elisa Shaholli
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Towards the Human Genotope [PDF]
, 2006 The human genotope is the convex hull of all allele frequency vectors that can be obtained from the genotypes present in the human population. In this paper we take a few initial steps towards a description of this object, which may be fundamental for ...
Huggins, Peter +2 more
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Archetypal Analysis of Injury in Kidney Transplant Biopsies Identifies Two Classes of Early AKI
Frontiers in Medicine, 2022 All transplanted kidneys are subjected to some degree of injury as a result of the donation-implantation process and various post-transplant stresses such as rejection.
Philip F. Halloran +11 more
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Affordances of Historic Urban Landscapes: an Ecological Understanding of Human Interaction with the Past [PDF]
, 2014 Heritage has been defined differently in European contexts. Despite differences, a common challenge for historic urban landscape management is the integration of tangible and intangible heritage. Integration demands an active view of perception and human-
Alves, Susana
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FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
CхідThe article explores the use of mythological narratives in Japanese animation as part of collective memory in the context of consumer culture. The author analyses symbolic and archetypal images in popular animated works such as Spirited Away, Gyakkyō ...
Roman Vorobei
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