Results 121 to 130 of about 568,927 (343)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Stages of development of Lenin Street in Chita
АрхитектонThe article reviews the process of development of Lenin Street, the central street of the city of Chita. The study has identified five key stages in the formation of the street’s architectural ensemble, defined by the general historical processes that ...
Semushina Irina S. +1 more
doaj +1 more source
Shifting Core and Slipping Foundation: An Uncertain Future of Landscape Architecture in European Universities [PDF]
, 2010 Faced with the dual and often conflicting necessity to be scientific and design practices the discipline of landscape architecture today is challenged to re-examine its core and intellectual foundation.
Koh, J.
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Refugee settlements and sustainable planning
Forced Migration Review, 2017 We need to develop refugee settlement planning processes that not only facilitate long-term planning but also allow for incremental upgrading. The case of M’Bera in Mauritania illustrates this.
Brett Moore
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Vanderbilt University’s West End Residential Colleges
Journal of Traditional Building, Architecture and UrbanismVanderbilt University’s West End residential colleges, in Nashville, Tennessee, were designed to enhance campus life through a blend of traditional Collegiate Gothic architecture and modern amenities. They include E.
Gregory Hoss, Steve Knight
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Refugees and the city: UN-Habitat’s New Urban Agenda
Forced Migration Review, 2017 Special protection for refugees and displaced persons should be part of countries’ housing policies.
Raffael Beier, Jasmin Fritzsche
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