Results 91 to 100 of about 124,140 (299)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
A camp redefined as part of the city
Was what was built at La Linière in Grand-Synthe in northern France a traditional refugee camp or a new kind of urban district?
Cyrille Hanappe
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Headquarters of the American Institute of Architects
1735 New York Avenue NW, Washington, DC ...
Architects Collaborative, Inc.
core
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Fire safety in high-rise buildings represents a critical challenge in the United Arab Emirates (UAE), where intensive urbanization, extreme climatic conditions, and multilayered regulatory frameworks impose unique competency demands on architects and ...
Salma Humaid Saeed Humaid Al Ali +5 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Stages of development of Lenin Street in Chita
The article reviews the process of development of Lenin Street, the central street of the city of Chita. The study has identified five key stages in the formation of the street’s architectural ensemble, defined by the general historical processes that ...
Semushina Irina S. +1 more
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Vanderbilt University’s West End Residential Colleges
Vanderbilt University’s West End residential colleges, in Nashville, Tennessee, were designed to enhance campus life through a blend of traditional Collegiate Gothic architecture and modern amenities. They include E.
Gregory Hoss, Steve Knight
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