Results 101 to 110 of about 124,140 (299)
Refugee settlements and sustainable planning
Forced Migration Review, 2017 We need to develop refugee settlement planning processes that not only facilitate long-term planning but also allow for incremental upgrading. The case of M’Bera in Mauritania illustrates this.
Brett Moore
doaj
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Sketch of Scott Hall, Pacific University
, 1966 Architect's sketch of the Harvey Walter Scott Memorial Library. The library was built in 1967 and named after the first graduate of Pacific University.
Dukehart & Kinne Architects, Artist
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Refugees and the city: UN-Habitat’s New Urban Agenda
Forced Migration Review, 2017 Special protection for refugees and displaced persons should be part of countries’ housing policies.
Raffael Beier, Jasmin Fritzsche
doaj
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
['Sustainability and Modernism: Design Research at Cornell NYC']
Docomomo Journal, 2011 Ilana Judah, Daniel Kaplan
doaj +3 more sources
Security of tenure in the urban context
Forced Migration Review, 2017 Addressing the lack of secure tenure and the risk of forced eviction is one of the defining characteristics of urban shelter response.
Neil Brighton +2 more
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source