Results 141 to 150 of about 124,140 (299)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Entropy as a Lens: Exploring Visual Behavior Patterns in Architects. [PDF]

J Eye Mov Res
Delucchi Danhier R, Mertins B, Mertins H, Schneider G.   +3 more
europepmc   +1 more source

Journal of the Royal Victorian Institute of Architects: 1926-1927

, 1926
Publication notes: Journal of proceedings (Royal Victorian Institute of Architects) Vol. 1 (1903/4)-v. 23, no. 6 (Jan. 1926); Continued by: Journal of proceedings of the Royal Victorian Institute of Architects Vol. 24, no.1 (Mar.
Royal Victorian Institute of Architects
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Continuity of care should be Dr Ian McWhinney's lasting legacy: Part 4 of the 10-part series, "Foundations for tomorrow". [PDF]

Can Fam Physician
Heath I.
europepmc   +1 more source

The world turned upside-down : architects as subcontractors in design-and-build contracts

, 2008
The traditional role of the Architect on UK building projects is well-known and has been the subject of much study and comment. However, recent surveys indicate that design-and-build arrangements now exceed traditional procurement in terms of their share
Greenwood, David, Walker, Alan, Walker, Peter   +2 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Journal of proceedings (Royal Victorian Institute of Architects): 1913-1914

, 1913
Publication notes: Journal of proceedings (Royal Victorian Institute of Architects) Vol. 1 (1903/4)-v. 23, no. 6 (Jan. 1926); Continued by: Journal of proceedings of the Royal Victorian Institute of Architects Vol. 24, no.1 (Mar.
Royal Victorian Institute of Architects
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Editorial: Molecular architects of the green world: genetic, epigenetic, and transcriptional regulation of plant metabolism and chemo-diversity. [PDF]

Front Plant Sci
Chen B, Zhao L, Ali S, Chishti S, Fujimoto R, Wang M, Liu F, Zhang Q.   +7 more
europepmc   +1 more source