Results 21 to 30 of about 14,357 (217)
Estudo da acessibilidade de idosos ao centro da cidade de Caratinga, MG
Revista Brasileira de Geriatria e GerontologiaEste estudo, ao abordar a questão da acessibilidade urbana dos idosos, traz à tona a discussão do planejamento do espaço urbano e a importância de se identificar as necessidades dos idosos em relação ao ambiente construído e em relação a seu deslocamento
Renato Campos Freire Júnior +3 more
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Cadernos Brasileiros de Terapia Ocupacional, 2019 Introduction: This article discusses physical accessibility and possible influences across users of an oncology service. Through the eyes of Occupational Therapy, we consider this as an important aspect before the rehabilitation process of these ...
Laura Bianchetti Galvan +3 more
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The relevance of Elvan Silva’s architectural discourse
ARQUISUR Revista, 2023 This article addresses the architectural design process by exploring different theoretical and practical perspectives. It analyzes issues such as user participation, the relationship between theory and practice, the pursuit of a universal architectural ...
Fernando dos Santos Calvetti
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Accessibility as a “Key Enabling Knowledge” to Human Development: the Accessibility Plan
Techne, 2014 In Italy, according to Law no. 41/1986 and Law no. 104/1992, public entities must draw up a Plan for Elimination of Architectural Barriers (PEBA). Unfortunately, many years after the introduction of these laws we can see that the PEBA is not yet a ...
Antonio Laurìa
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Iconarp International Journal of Architecture and Planning, 2022 The study's major objective is to demonstrate that historical structures and locations are completely accessible to all people. While the required architectural modifications are performed in historic buildings and locations, they are intended to ...
Mehmet Akif Çelimli, Murat Oral
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
ValeAS: an ICT tool to assess accessibility and safety of the built environment
Techne, 2014 ValeAS (Assessment of Accessibility and Safety) is a software developed by the Construction Technologies Institute, Rome Unit, of the National Research Council (ITC-CNR), with the aim of giving an ICT tool for assessing the accessibility level of egress ...
Luigi Biocca +3 more
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