Results 31 to 40 of about 19,172 (304)
Iconarp International Journal of Architecture and Planning, 2022 The study's major objective is to demonstrate that historical structures and locations are completely accessible to all people. While the required architectural modifications are performed in historic buildings and locations, they are intended to ...
Mehmet Akif Çelimli, Murat Oral
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Accessible enough? : Legitimising half-measures of accessibility in Swedish urban environments
, 2022 This chapter aims to contribute with an understanding of how inaccessibility is legitimised and normalised in Swedish cities even when it is tangible and well-known to the authorities. Although independent and equal access is the overarching principle of
Egard, Hanna, Egard, Hanna,
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Accessibility as a “Key Enabling Knowledge” to Human Development: the Accessibility Plan
Techne, 2014 In Italy, according to Law no. 41/1986 and Law no. 104/1992, public entities must draw up a Plan for Elimination of Architectural Barriers (PEBA). Unfortunately, many years after the introduction of these laws we can see that the PEBA is not yet a ...
Antonio Laurìa
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Augmented Reality for the accessibility of architectural archive drawings
, 2023 The cultural heritage represented by architectural drawings kept in public and private Italian archives has been the subject of attention by the contexts institutionally responsible for their conservation and archiving. With the progressive establishment
Matteo Flavio Mancini +2 more
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Architectural and planning solutions for multistorey residential buildings with safety capsules [PDF]
E3S Web of ConferencesThe purpose of this study is to develop an architectural and construction solution for protecting the civilian population in a multi-story residential building by creating a safe space with instant accessibility.
Bordun Maryna +4 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source