Results 51 to 60 of about 135,513 (312)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Glazkovo Spit (Zaton): problems and future development

Проект Байкал, 2018
The article presents projects worked out in different years by architectural students under the supervision of the architects Lyubov Nikolaevna Makogon and Roman Alexandrovich Selivanov, assistant professors of the Department of Architectural Design of ...
Lyubov Makogon, Roman Selivanov
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Measuring physical disorder of architectural façades for informing better urban renewal using deep learning and space syntax

Frontiers in Sustainable Cities
With the emergence of human-centered urban development goals and the increasing pursuit of a better quality of life, the architectural façades of cities are receiving growing attention.
Huiyue Xing, Haojun Shi, Yufan Sun
doaj   +1 more source

Multiple-PON access network architecture [PDF]

2nd IET International Conference on Access Technologies, 2006
A novel access network architecture based on a coarse wavelength division multiplexing array waveguide grating router for switching up to 32 optical network units per passive optical network over a single coarse wavelength band is described. The cost effective network architecture is simulated, using a physical-layer model of two passive optical ...
Y. Shachaf, P. Kourtessis, J.M. Senior
openaire   +1 more source

Ancient Cartographies as a Basis for Geolocation Models in Public Space: The Case of Giambattista Nolli and its Heritage Application [PDF]

, 2019
In 1748, the architect and surveyor Giambattista Nolli mapped an abstract reality of the city of Rome. As a challenge to the inherited projections, it represented the city mixing streets, halls, corridors, churches, baths and markets as part of a unique ...
Cubero Hernández, Antonio, Mosquera Pérez, Clara, Navarro De Pablos, Francisco Javier   +2 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Acessibilidade aos serviços de saúde: uma análise a partir da Atenção Básica em Pernambuco

Saúde em Debate
Analisou-se a acessibilidade aos serviços de saúde de Atenção Básica em Pernambuco e os aspectos que favorecem ou dificultam a entrada e a permanência do usuário no sistema de saúde.
Maria do Socorro Veloso de Albuquerque, Tereza Maciel Lyra, Sidney Feitoza Farias, Marina Ferreira de Medeiros Mendes, Petrônio José de Lima Martelli   +4 more
doaj   +1 more source

ValeAS: an ICT tool to assess accessibility and safety of the built environment

Techne, 2014
ValeAS (Assessment of Accessibility and Safety) is a software developed by the Construction Technologies Institute, Rome Unit, of the National Research Council (ITC-CNR), with the aim of giving an ICT tool for assessing the accessibility level of egress ...
Luigi Biocca, Antonio D’Eredità, Ludovica Malavasi Caula Medici, Nicolò Paraciani   +3 more
doaj   +1 more source