Results 51 to 60 of about 19,172 (304)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
An Architectural Self - Criticism: The Accessibility Analysis of Berlika Park Swimming Pool
Iconarp International Journal of Architecture and Planning, 2016 Urban designers and architects have to clearly understand the physical features and needs of the people they are designing for. In the designing process fields such as anthropometry, biomechanics, ergonomics, biology and physics require scientific ...
Özlem Demirkan
doaj +3 more sources
Glazkovo Spit (Zaton): problems and future development
Проект Байкал, 2018 The article presents projects worked out in different years by architectural students under the supervision of the architects Lyubov Nikolaevna Makogon and Roman Alexandrovich Selivanov, assistant professors of the Department of Architectural Design of ...
Lyubov Makogon, Roman Selivanov
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
, 2022 © 2022 Architectural Institute of Korea.This study proposes a method to derive an optimal alternative to the reinforcement point factoring indoor accessibility by evaluating the physical protection system for architectural facilities with many internal ...
신재섭, 최재필
core +1 more source
SecurSight: an architecture for secure information access [PDF]
Proceedings 15th Annual Computer Security Applications Conference (ACSAC'99), 2003 This paper describes SecurSight, an architecture that combines authentication, authorization, and secure communications. The primary goal of this architecture is to secure access to network resources, while providing a smooth migration path from legacy authentication and authorization methods to a public-key infrastructure.
openaire +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source