Results 61 to 70 of about 19,172 (304)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Frontiers in Sustainable CitiesWith the emergence of human-centered urban development goals and the increasing pursuit of a better quality of life, the architectural façades of cities are receiving growing attention.
Huiyue Xing, Haojun Shi, Yufan Sun
doaj +1 more source
An abstract dynamic access control architecture
Journal of Applied Logic, 2011 AbstractThis paper presents an abstract architecture capturing the most essential characteristics of security architectures for the kind of access control required in multi-agent systems. A security architecture is usually component based; it is dynamically extensible, reflective, and should be able to support a variety of policy strategies and ...
Chuchang Liu +2 more
openaire +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Swimming Pool Accessibility Final Report
, 1996 Final report on the swimming pool accessibility studyU.S.
Hamilton, Edward J. +2 more
core
Raising Awareness about Accessibility [PDF]
, 2012 Every citizen has to right to move throughout a city safely and independently. The term accessibility refers this right in built environment mostly for public uses. In the beginning of 20th century, accessibility started from a restricted application but
Evcil, Ayse Nilay
core +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Swimming Pool Accessibility Recommendations and Product Information
, 1996 Recommendations and product information from the pool accessibility study that informed the standards on the subject.U.S.
Hamilton, Edward J +2 more
core