Results 81 to 90 of about 1,004,085 (305)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Публічне управління та регіональний розвитокThe article analyzes the experience of foreign countries in the field of architectural accessibility for people with limited mobility and the possibilities of its adaptation in Ukraine.
Svitlana Surgova, Olena Faichuk
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Inclusão da pessoa com deficiência em um Centro de Referência em DST/AIDS de um município baiano
Revista Brasileira de EnfermagemO presente estudo, de abordagem qualitativa, buscou conhecer a opinião dos profissionais de saúde sobre a inclusão das pessoas com deficiência nas atividades de acolhimento, prevenção e tratamento em um Centro de Referência em DST/AIDS.
Alessandra Santos Sales +2 more
doaj
A Conceptual Model for Born-Accessible Web Accessibility Regeneration Using Large Language Models
ComputersWeb accessibility remediation using large language models (LLM) has recently gained attention; however, most approaches remain tool-centric and lack formal architectural grounding.
Guillermo Vera-Amaro +1 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Using open accessibility data for accessible travelling
, 2014 This paper summarizes the research of using open accessibility data for accessible travelling. With the aim of addressing the gap between users’ special needs and complex accessibility barriers in real world, we proposed a personalized accessible ...
Ding, Chaohai, Wald, Mike, Wills, Gary
core +1 more source
This study uses accessibility as a performance measure to evaluate a matrix of future land use and network scenarios for planning purposes. Previous research has established the coevolution of transportation and land use, demonstrated the dependence of ...
Paul Anderson +2 more
core