Results 71 to 80 of about 135,513 (312)

An Architectural Self - Criticism: The Accessibility Analysis of Berlika Park Swimming Pool

Iconarp International Journal of Architecture and Planning, 2016
Urban designers and architects have to clearly understand the physical features and needs of the people they are designing for. In the designing process fields such as   anthropometry, biomechanics, ergonomics, biology and physics require scientific ...
Özlem Demirkan
doaj   +3 more sources

The Functional Transformation Buildings in The Old City Semarang Based on The Urban Sustainable-Conservation Concepts [PDF]

, 2013
Conservation and Sustainability are inspiring the region of the Old City in Semarang. As the meanings of both words, the aim of conservation and sustainability in this region is addressed to secure long-term harmony between man and nature, to achieve ...
Setyowati, Erni
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Selected Aspects of the Tourist Space of the Lublin Region (Case Study) [PDF]

, 2014
The article presents the results of studies on the tourist space of the Lublin Region conducted so far by employees of the Department of Regional Geography and Tourism at the Faculty of Earth Sciences and Spatial Management of the Maria Curie-Skłodowska ...
Brzezińska-Wójcik, Teresa, Jóźwik Marta, Jolanta, Krukowska, Renata, Skowronek, Ewa, Tucki, Andrzej, Świeca, Andrzej   +5 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Looking Good, Feeling Good – Tac Map: a navigation system for the blind [PDF]

, 2011
This paper describes the research and development of a navigation system for the blind that provides a tactile and visual language that can be understood by both sighted and blind users.
Chamberlain, Paul, Dieng, Patricia
core  

Random Walks Along the Streets and Canals in Compact Cities: Spectral analysis, Dynamical Modularity, Information, and Statistical Mechanics [PDF]

, 2006
Different models of random walks on the dual graphs of compact urban structures are considered. Analysis of access times between streets helps to detect the city modularity.
B. Hillier, B. Hillier, D. Cvetkovic, D. Volchenkov, E. Nelson, J. Nieminen, J. P. Steadman, L. Lovász, L. Lovász, L. March, M. Fiedler, M. Fiedler, P. Hagget, Ph. Blanchard, Ph. Blanchard, S. Wasserman, W. Feller, Y. Colin de Verdiére   +17 more
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The development of accessibility indicators for distance learning programs [PDF]

, 2006
A study was undertaken to explore program policies and practices related to the accessibility of American distance learning courses to qualified students with disabilities.
Burgstahler, Sheryl
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source