Results 71 to 80 of about 5,579,145 (316)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Architectural year book, University of Illinois. 9 [PDF]
, 1911 None issued 1918-1920 inclusive.Published -1917 by the Architectural Club; 1921- by the Architectural ...
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
The Architectural year book, University of Illinois. 4 [PDF]
, 1911 None issued 1918-1920 inclusive.Published -1917 by the Architectural Club; 1921- by the Architectural ...
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Barriers to BIM Adoption in Design Practice: A Systematic Review of Developing Countries
Nature: National Academic Journal of ArchitectureDespite the progress made with BIM integration into the construction industries of many developed countries, its adoption remains limited in most developing countries.
Daniel Ebo Hagan +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Actors and Vehicles of Architectural Criticism (2)
, 2016 The Role of Architectural Journals between Medium and the Message Jasna Galjer University of Zagreb The paper explores the case studies of the professional journals in the context of promoting new architectural language and their multilayered roles; from
Mapping Architectural Criticism
core +1 more source
The Architectural year book, University of Illinois. 15 [PDF]
, 1911 None issued 1918-1920 inclusive.Published -1917 by the Architectural Club; 1921- by the Architectural ...
core +1 more source