Results 81 to 90 of about 5,579,145 (316)
Why Architectural History Struggles to Integrate with the Design Studio
Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUAThe architectural design studio is located at the centre of the learning expected in the Bachelor of Architecture course. It is expected that all other subjects must inform and enrich the learning in the design studio.
Shalini Sheoran, Manoj Panwar
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
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The Architectural year book, University of Illinois. 7 [PDF]
, 1911 None issued 1918-1920 inclusive.Published -1917 by the Architectural Club; 1921- by the Architectural ...
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PARC: Pesquisa em Arquitetura e Construção, 2014 This paper presents an analysis of the Building Information Modeling implementation process in architectural and industrial design companies in Belo Horizonte.
Miguel Pereira Stehling +1 more
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
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Cornucopia Reloaded: Load Barriers for CHERI Heap Temporal Safety
International Conference on Architectural Support for Programming Languages and Operating SystemsViolations of temporal memory safety ("use after free", "UAF") continue to pose a significant threat to software security. The CHERI capability architecture has shown promise as a technology for C and C++ language reference integrity and spatial memory ...
N. Filardo +11 more
semanticscholar +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
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