Results 111 to 120 of about 48,265 (304)
Advanced Healthcare Materials, EarlyView.ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett +7 more
wiley +1 more source
Global experts 'off radar' [PDF]
, 2014 This issue of ABE Journal, which takes inspiration from a 2008 conference session as well as from the many conversations that took place within one of the working groups of the European funded COST-action “European Architecture beyond Europe,”1 seeks to ...
De Raedt, Kim, Lagae, Johan
core +1 more source
Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids
Advanced Healthcare Materials, EarlyView.Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López +5 more
wiley +1 more source
Ambiguities in Terminology and Taxonomy as Factors in the Marginalization of Architectural Styles
ABE Journal, 2012 Davy Depelchin
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan +12 more
wiley +1 more source
The Unsung of the Canon: Does a Global Architectural History Need New Landmarks?
ABE Journal, 2015 Sibel Zandi-Sayek
doaj +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, EarlyView.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Microengineered Gradient Hydrogels for Mechanobiology
Advanced Healthcare Materials, EarlyView.Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong +4 more
wiley +1 more source
„Fabryki ruchu”. Z problematyki dworców kolejowych w Polsce w latach 60. i 70. XX wieku
Miejsce, 2016 The work of architects employed during the communist regime in Polish state design offices, which significantly influenced the shape of the contemporary built environment, is often perceived as self-evident, worthless, and rarely is a subject of deep ...
Alicja Gzowska
doaj