Results 161 to 170 of about 1,897 (296)

Digital subtraction pancreatography enhances ductal visualization in high grade pancreatic intraepithelial neoplasia. [PDF]

Endoscopy
Maruyama A, Takano K, Yamada J, Kato H, Isobe S, Kobayashi M.   +5 more
europepmc   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Shuffling the Canon: Towards a decolonized understanding of Architecture

Dearq, 2023
Fernando Luiz Lara, Fernando Luis Martínez Nespral, Ingrid Quintana-Guerrero   +2 more
openaire   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source

Comparing YOLO and U-net deep learning algorithms in chronic wound image segmentation. [PDF]

BMC Med Imaging
Marchal I, Ali Z, Ammi H, Smet S, Van de Voorde L, Varon C, Ngan Yamb MA, Yunda Sangoluisa JA, Quitin F, Nonclercq A.   +9 more
europepmc   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Multi-storey modular manoeuvres : Innovative architectural stacking methodology based on three Swedish timber building systems

, 2012
The authors present a logical outline for an innovative architectural stacking methodology based on three Swedish timber construction systems. They discuss the increased architectural–engineering quality, sustainable advantages, and cost effectiveness of
Girhammar, Ulf Arne, Kaiser, Alex, Larsson, Magnus   +2 more
core  

Digital restoration and feature recognition of a Qing-Dynasty vernacular dwelling based on multimodal data fusion. [PDF]

Sci Rep
Xia X, Chen Z, Xu Y.
europepmc   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

The Grand Canon Of The Colorado.

, 1902
THE GRAND CANON OF THE COLORADO1 BY JOHN MUIR Author of The Mountains of California Our National Parks etc. HAPPY nowadays is the tourist, with earth\u27s wonders, new and old, spread invitingly open before him, and a host of able workers as his ...
Muir, John
core