Results 191 to 200 of about 48,265 (304)

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

open access: yesAdvanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei   +15 more
wiley   +1 more source

Robot-Assisted Peripheral Retinal Visualization during Vitrectomy without Scleral Depression: A First-In-Human Comparative Study. [PDF]

open access: yesOphthalmol Sci
Ashikaga K   +6 more
europepmc   +1 more source

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

open access: yesAdvanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen   +7 more
wiley   +1 more source

Decision-OS V6 (PIC): Canonical Memory Architecture for Self-Recursive Intelligence

open access: yes
We present SiriusA-PIC, a phase-invariant memory architecture reframing “context engineering” as structural intelligence. A global state S is updated by monotone deltas (ΔS) from independent modules; states are merged via a commutative, associative, and idempotent join (⊔) and then Canonicalized. Safety is encoded as defaults: severity ordering (PASS <
openaire   +3 more sources

Artificial intelligence based retinal imaging for cardiovascular risk and statin guidance in retinal vein occlusion. [PDF]

open access: yesAm J Prev Cardiol
Nam D   +7 more
europepmc   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

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