Results 61 to 70 of about 48,001 (282)
Известия Уральского федерального университета. Серия 2: Гуманитарные науки, 2016 The paper considers the potestary symbols of a Soviet person’s everyday life. The Soviet government did not only work towards a total control of production, but also of private life.
Elena Vladimirovna Barysheva
doaj +1 more source
Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase [PDF]
Nature Communications, 2015 AbstractRadical S-adenosylmethionine (SAM) enzymes use a [4Fe-4S] cluster to generate a 5′-deoxyadenosyl radical. Canonical radical SAM enzymes are characterized by a β-barrel-like fold and SAM anchors to the differentiated iron of the cluster, which is located near the amino terminus and within the β-barrel, through its amino and carboxylate groups ...
Fenwick, Michael K. +5 more
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Essay: Hanoi: La Folie des Grandeurs [PDF]
Pacific Geographies, 2019 Around the time Admiral Charles Rigault de Genouilly, under the orders of Emperor Napoléon III, fired the first canon shots to lay claim to what would become France’s colony of Indochina, Paris embarked on an epic renovation project directed by Baron ...
Burchett, George
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Modernist Architecture and Ruins [PDF]
, 2019 Modernist Architecture and Ruins: On Ruins as a Minus, Neoclassicism and the ...
Kurir, Mateja
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Miejsce ekfrazy w bizantynistycznej historiografii artystycznej
Vox Patrum, 2018 In Byzantium, writing ekphrases was one of the standard literary skills, developed during school instruction. Yet, in Byzantine art history, the analysis of Byzantine ekphrases had long been beyond the scope of researchers who favoured rather the ...
Małgorzata Smorąg Różycka
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
At hylde arkitekturen. Bygningspræmiering som kritisk praksis
Periskop, 2019 Architectural critique is often considered to be in a long-term crisis. Suggested causes are theoretical changes to the role of the critic, as well as reviews being expelled from a changing media landscape.
Martin Søberg, Morten Birk Jørgensen
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