Results 61 to 70 of about 1,897 (296)
Between Populism and Dogma: Álvaro Siza’s Third Way
Footprint, 2011 In the early 1980s, Kenneth Frampton presented critical regionalism as an umbrella concept to frame some peripheral architectural practices that became instrumental to illustrate an alternative approach both to the modernist dogma and to post-modernist ...
Nelson Mota
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Towards a canonical software architecture for multi-device WebLabs [PDF]
31st Annual Conference of IEEE Industrial Electronics Society, 2005. IECON 2005., 2005 Traditionally the focus on WebLab design has been placed on the hardware side, i.e. enabling data and program transfer between a PC remotely accessible through TCP/IP and its attached controllable/programmable device. Little attention has been paid to the other communication segment going from the controlling PC (WebLab server) and the remote users ...
J. Garcia-Zubia +2 more
openaire +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
unboxing the canon - Episode 4: Swallowed Whole
, 2020 In this episode, called “Swallowed Whole,” Dr. Steer considers Gothic cathedrals as an art form and examines their relationship to European power structures.
Steer, Linda
core
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Exclusive Histories, Unseen Narratives
Architektúra & UrbanizmusThe canon is generally understood as a body of the most important personalities and key works in a particular field, and for various reasons it evokes an impression of objectivity and impartiality.
Klára Brůhová
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
THE COMBINATION OF THE IMAGE AND RANGE-BASED 3D ACQUISITION IN ARCHAEOLOGICAL AND ARCHITECTURAL RESEARCH IN THE ROYAL CASTLE IN WARSAW [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019 The paper presents archaeological and architectural research in the Royal Castle in Warsaw where a combination of image- and range-based 3D acquisition was applied.
A. Bocheńska +2 more
doaj +1 more source
A History of Urbanism in Europe
, 2021 A sound understanding of how our built environment came about constitutes a core competence in any architectural training and professional experience. The history of urbanism on the European continent, in particular, constitutes a fundamental basis for ...
Sterken, Sven +3 more
core