Results 141 to 150 of about 2,883,041 (303)
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
A post-structural analysis of the architectural education - technology relationship [PDF]
, 2004 This dissertation investigates how technology and architectural education relate to each other, in the broadest possible sense. What are the internal and external factors affecting our understanding and use of technology in architectural education?
Özersay, Fevzi
core +1 more source
Proceedings of the International Conference on Applied Innovations in ITThe use of digital technologies for the digitisation and virtual reconstruction of architectural heritage has gained global relevance. This paper presents the initial stage of a scientific and practical study aimed at digitally reconstructing the 15th ...
Nilufar Tukhboeva +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Remote SensingBuilt heritage materials assessment is an important task for planning and managing future conservation works. The uniqueness of each historical building makes reconnaissance operations more complex and specific for every single building.
Maria Alicandro +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
News : Workshop, Mapping Architectural Criticism in China
, 2018 The workshop Mapping Architectural Criticism in China was held at the Department of Architecture, Xi'an Jiaotong-Liverpool University on April 24, 2018. You can download the full programme of the workshop here.
Mapping Architectural Criticism
core
News : Colloquium, 13 - 14 september 2022 : Architectural criticism, Medias and Memory
, 2022 ARCHITECTURAL CRITICISM, MEDIAS AND MEMORY is a colloquium to be held on 13‒14 September 2022 at the office of the Council of Architecture and Urbanism, Rio de Janeiro session (CAU-RJ).
Mapping Architectural Criticism
core
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source