Results 121 to 130 of about 40,506 (313)
A web-based system for collaborative electro-acoustic composition
This paper describes development of an online system for collaborative electro-acoustic music composition. Traditionally, software systems for music composition have been single user systems.
Dovey, Matthew, Gibson, Ian
core +1 more source
Architectural applications for composites
Abstract Composites can offer a number of advantages in architectural applications and it's surprising that they're not used more widely.
openaire +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
The Nordic tradition of architectural competitions is over a hundred years old and is very significant for an architect’s professional and practical external training.
Rönn, Magnus,
core
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Investigating the mathematical and geometric principles embedded in ancient classic architecture is a significant tradition in the history of architectural development.
Shusheng Wang +5 more
core +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Patterns & Variations: Designerly Explorations in Architectural Composition and Perception
How can we better understand and explain the phenomena of architectural composition and perception? The aim of this research is to systematically and imaginatively (re)consider the conditions of architectural composition, whilst doing justice to the ...
Breen, J.L.H., Breen, J.L.H. (author)
core +1 more source

