Results 111 to 120 of about 2,883,041 (303)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Technology Architectural Review [PDF]
Publication of the Massachusetts Institute of Technology Architectural Society. Volume 3.
Massachusetts Institute of Technology. Department of Architecture +1 more
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Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Actors and Vehicles of Architectural Criticism (1)
Actors of Criticism: How the Editors of AD Magazine shaped Architecture Stephen Parnell Newcastle University From its establishment in 1930, architect John Kendall briefly edited Architectural Design (AD) magazine until his death in 1934 when Frederic ...
Mapping Architectural Criticism
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FANTASY FIGURE IN CREATIVE INDEPENDENT WORK OF STUDENTS-ARCHITECTS
It is considered that one of the most urgent problems of architectural education - creative development of students in the course of independent work on a drawing class.
V. P. Mamugina
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Architectural Criticism between Public Debate and Autonomous Discipline (6)
Mobilizing the Nation via Architectural Criticism : The Architectural Review “Outrage” and “Counterattack” Erdem Erten Associate Professor, Izmir Institute of Technology, Department of Architecture In June 1955, The Architectural Review’s special issue ...
Mapping Architectural Criticism
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