Results 31 to 40 of about 2,881 (264)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Visual Narratives of Change: Examining Students’ Drawings and Teaching Transformations at MIT

open access: yesTrends in Higher Education
Since its inception, the Massachusetts Institute of Technology (MIT, Cambridge, MA, USA) has preserved student drawings and design projects as educational tools and reference materials.
Rafael Sousa Santos   +3 more
doaj   +1 more source

Drawings on paper. Digital historical archives of the former Radaar Department at the University Sapienza School of Architecture in Rome

open access: yesSCIRES-IT, 2014
The paper presents the work now being carried out to develop digital archives of the historical drawings amassed by the former Department of Architectural and Environmental Surveying, Analysis and Drawing (Radaar) at the University Sapienza School of ...
Emanuela Chiavoni
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

A Grammar of Muqarnas: Drawings of the Alhambra by Jones and Goury (1834-1845)

open access: yesVLC Arquitectura, 2019
The muqarnas of the Nasrid Alhambra stand out as one of the most singular architectural episodes of Medieval Islamic art due to their sophisticated three-dimensional construction, whose layout remains little known.
Antonio Gámiz Gordo   +1 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Proportional Design Systems in Seventeenth-Century Holland

open access: yesArchitectural Histories, 2014
This article focuses on architectural drawings, some only recently discovered, that contain indications of authentic proportional systems from the ‘inner circle’ of Dutch seventeenth-century classical architecture.
Konrad Ottenheym
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Representation as Mental Projections: De/Re-constructing Casa della Falsità through Sequential Transformations [PDF]

open access: yesSHS Web of Conferences
This study investigates architectural representation as a dynamic “mental projection” exploring where geometric logic and conceptual thought intersect.
Yavaş Hülya
doaj   +1 more source

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