Results 41 to 50 of about 16,812 (314)

Fábio Moura Penteado in São Paulo. Drawings for a Modern, Urban, and Democratic Architecture

open access: yesDiségno, 2023
Drawings represent ideas and concepts, not just an architectural project. The concept of the ‘Architecture of the Crowd’ establishes principles of an architecture in which people are protagonists.
Letícia Bortolo Martins, Ana Tagliari
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

The story of another way of drawing. Structuralist architectural drawings in Het Speelhuis by Piet Blom

open access: yesBulletin KNOB, 2018
Dutch Structuralism was an influential tendency in post-war Dutch architecture and urban design. Structuralist designs and buildings are made up of repetitive elements that can in theory be adjusted in both size and function.
Ellen Smit
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

THE SPIRITUAL CONSISTORY IN VLADIVOSTOK: ARCHITECTURAL PROJECTS AND IMPLEMENTATION

open access: yesАрхитектон, 2021
The article is devoted to the history of the architecture of pre-revolutionary Vladivostok and, in particular, its ecclesiastical consistory, the administrative office of the diocese. The publication is largely based on archival material from the Russian
Tolkacheva Albina A., Likhansky Yury I.
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

To See (Like) a Crowd

open access: yesArchitectural Histories, 2015
This paper explores the dynamics through which design drawings structure spatial strategies, particularly those with an agenda for socio-political change, while interrogating the drawings’ impacts on subjectivity.
Hazem Ziada
doaj   +3 more sources

The Drawings of The Wilanow Collection of the Potocki Family in the National Library in Warsaw, Organisation, Album Structure and Condition

open access: yesToruńskie Studia Bibliologiczne, 2016
Among the graphic collection of the Polish National Library's in Warsaw stands out “Wilanów Collection”, a part of Wilanów Library holdings, which were given to the National Library in 1932. It is noteworthy because of the substantive content, as well as
Katarzyna Garczewska-Semka
doaj   +1 more source

What Do Large Language Models Know About Materials?

open access: yesAdvanced Engineering Materials, EarlyView.
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer   +2 more
wiley   +1 more source

Il disegno come teoria

open access: yesRivista di Estetica, 2019
The paper combines a question about the architectural design project with the topics of future and utopia, through a series of drawings made all along the author’s career.
Franco Purini
doaj   +1 more source

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