Results 21 to 30 of about 4,478 (261)

The first year of architectural education

Проект Байкал, 2023
The article reflects the dissatisfaction with the situation in the process of training future architects. The apparent crisis of the architectural profession has been caused not only by external factors, decreasing its prestige, but also by internal ...
Алексей Буйнов, Армен Казарян   +1 more
doaj   +1 more source

Transformed Shell Roof Structures as the Main Determinant in Creative Shaping Building Free Forms Sensitive to Man-Made and Natural Environments

Buildings, 2019
The article presents author’s propositions for shaping free forms of buildings sensitive to harmonious incorporation into built or natural environments. Complex folded structures of buildings roofed with regular shell structures are regarded as the
Jacek Abramczyk
doaj   +1 more source

High-Definition Survey of Architectural Heritage Fusing Multisensors—The Case of Beamless Hall at Linggu Temple in Nanjing, China

Sensors, 2022
Following the development of digital measurement technology in recent years, the information contained in the measurement outcomes have become increasingly rich.
Junwei Fang, Yingying Zhang, Yiru Zhang, Huayu Guo, Zheng Sun   +4 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Determination of Efficiency of the Vertical Specularly Reflecting Cylindrical Light Shaft for Different Types of Firmaments

Journal of Daylighting
Article is devoted to determination of efficiency of the vertical specularly reflecting cylindrical light shaft for various types of the firmaments standardized by CIE (International Commission on Illumination).
Serhii Litnitskyi, Eugene Pugachov, Taras Kundrat, Vasyl Zdanevych   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Aesthetical Appeal and Dissemination of Architectural Heritage Photographs in Instagram

Buildings, 2020
Image-based social networks are environments where users share their photographs and involuntarily contribute to evolve and to spread the meaning of things.
Vicente López-Chao, Vicente Lopez-Pena
doaj   +1 more source