Results 41 to 50 of about 761,173 (302)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The changing patterns of architectural design education [PDF]
, 2008 Digital technologies have been introduced to students of architecture for over two decades and at present it could be argued that students are producing some of the highest quality designs, and some of the most interesting forms ever to come from ...
Horne, Margaret, Giddings, Bob
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Decoupled Sampling for Real-Time Graphics Pipelines [PDF]
, 2010 We propose decoupled sampling, an approach that decouples shading from visibility sampling in order to enable motion blur and depth-of-field at reduced cost.
Ragan-Kelley, Jonathan +4 more
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Three Point Lighting Design Automation for Computer Graphics
, 2012 [[abstract]]In this paper, we will discuss the possibility of automating the process of lighting setup in computer graphics. We focus on a well-established technique known as “three-point lighting”. We devised a process of lighting setup automation based
Su Ian Eugene Lei;Chun-Fa Chang
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
, 2021 Hélène Jannière and Paolo Scrivano, scientific coordinators of Mapping Architectural Criticism, are very pleased to announce the forthcoming International Conference on Architectural Criticism, On the Duty and Power of Architectural Criticism.
Mapping Architectural Criticism
core
Inventive Methods in Conceptual Architectural Design
Education SciencesIn architectural design, the conceptual phase is of particular importance, as it plays a crucial role in achieving ambitious goals and creating valuable design concepts.
Igor Labuda, Jolanata Dzwierzynska
doaj +1 more source
Integrated Parametric Shaping of Curvilinear Steel Bar Structures of Canopy Roofs
Buildings, 2019 Shaping building objects is conditioned by many interrelated factors, both architectural and structural. Modern tools for shaping structures working in the environment of Rhinoceros 3D such as Grasshopper and Karamba 3D enable algorithmic-aided shaping ...
Jolanta Dzwierzynska
doaj +1 more source