Results 71 to 80 of about 761,173 (302)

The Concrete Shells of Felix Candela [Exhibition Description]

open access: yes, 1961
Description for the Felix Candela Exhibition, January 28–February 28, 1962, at the Dallas Museum of Fine ...
Architectural Graphics
core  

Assessment and the graphics calculator [PDF]

open access: yes, 1995
As graphics calculators become more accessible, issues of assessment will become more important. The main reason for this is that graphics calculators provide students with significant mathematical capabilities, some of which are described here.
Kissane, B., Bradley, J., Kemp, M.
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

FROM THE BASICS OF SPATIAL CONSTRUCTIONS TO CONSTRUCTION OF AN IMAGE (A CASE STUDY OF ENGRAVINGS BY GIOVANNI BATTISTA PIRANESI)

open access: yesArchitecture and Engineering, 2016
The article deals with the exhibition “Piranesi. Before and After. Italy—Russia. XVIII–XXI Centuries” held at the Pushkin State Museum of Fine Arts in Moscow in autumn, 2016.
Elena Chernaya
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

The architecture of the Smolensk fortress wall in iconography

open access: yesАрхитектон
The architectural heritage of the largest brick fortress in the world - the Smolensk Fortress Wall - has found a notable reflection in various fine arts.
Sergey A. Pilyak
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Graphics calculators and algebra [PDF]

open access: yes, 1999
The personal technology of the graphics calculator is presently the only one likely to be available widely enough to influence curriculum design and implementation on a large scale.
Kissane, B.
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

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