Results 61 to 70 of about 455,051 (282)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Architectural design education through history of architecture: the lesson of Bruno Zevi [PDF]
, 2014 Ponencia presentada a Session 3: Educación y arquitectura en las universidades / Architectural education in the universitiesBruno Zevi, born in 1918 and died in 2000, is one of the most important Italian theorists of architecture.
Ardizzola, Paola
core
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
J@rgonia, 2019 A book review of: Hämeenaho, Pilvi, Tiina Suopajärvi & Johanna Ylipulli (eds.). Soveltava kulttuurintutkimus. Helsinki: Suomalaisen Kirjallisuuden Seura. 2018. 328 s.
Kalakoski, Iida
doaj
THE HOLLY QURAN ENCOURAGE RESEARCH IN ARCHITECTURAL HISTORY
Journal of Engineering, 2010 The science of architectural history is considered one of the basic fields of the architectural studies because it reflects civilization, intelligence and creation .The present research problem takes to account the confusion image of the importance of ...
حفصة رمزي ألعمري +1 more
doaj +1 more source
Rediscovering architecture : paestum in eighteenth-century architectural experience and theory, by Sigrid de Jong [PDF]
, 2018 Book review of: Sigrid de Jong, Rediscovering Architecture: Paestum in Eighteenth-Century Architectural Experience and Theory. New Haven, Conn.: Yale University Press, 2015, 352 pp., 100 color and 185 b/w illus.
De Meyer, Dirk
core +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
St. Mary’s Episcopal Church: Architectural History and Preservation Possibilities [PDF]
, 2017 This thesis focuses on the architectural and historical significance of St. Mary’s Episcopal Church in Portsmouth, Rhode Island. It comprises two major sections: a historical narrative and a research narrative. Thus, it is meant to illuminate the history
O’Neill, Anastasia
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Expert systems and the emergence of teledesign [PDF]
, 2001 This paper considers the extent to which the amateur use of expert systems for home design challenges traditional views of the design process. The issues are examined in the context of competing definitions of design.
Crabbe, A
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source