Results 91 to 100 of about 228,900 (283)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The changing patterns of architectural design education [PDF]
, 2008 Digital technologies have been introduced to students of architecture for over two decades and at present it could be argued that students are producing some of the highest quality designs, and some of the most interesting forms ever to come from ...
Giddings, Bob, Horne, Margaret
core
, 2007 Enterprise Modelling and Information Systems Architectures, Vol 2, No 1 (2007)
Arbab, F. +5 more
openaire +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Digitally Archiving Architectural Models and Exhibition Designs: The Case of an Art Museum [PDF]
, 2015 [Excerpt] In 2013, a medium-sized art museum located in the Northeast United States received a grant to plan for an electronic records repository. This museum will be referred to here as USAM for brevity.
Cocciolo, Anthony
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Software dependability modeling using an industry-standard architecture description language
, 2008 Performing dependability evaluation along with other analyses at architectural level allows both making architectural tradeoffs and predicting the effects of architectural decisions on the dependability of an application.
Feiler, Peter H. +3 more
core +2 more sources
Using ontologies for modeling context-aware services platforms [PDF]
, 2003 This paper discusses the suitability of using ontologies for modeling context-aware services platforms. It addresses the directions of research we are following in the WASP (Web Architectures for Services Platforms) project.
Dockhorn Costa, P. +5 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source