Results 71 to 80 of about 3,016,747 (301)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Architectural year book, University of Illinois. 9 [PDF]
, 1911 None issued 1918-1920 inclusive.Published -1917 by the Architectural Club; 1921- by the Architectural ...
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Frontiers of Architectural ResearchThe present research studies the relationship between place attachment and the perception of form's visual quality in fifteen outstanding contemporary Iranian architectural cultural buildings.
Narmin Ariannia +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2016 Software systems tend to increase over time in size and complexity. Their development usually spans a long period of time and often results in systems that are hard to understand, debug and maintain. Architectures are common means for organising coordination between components in order to build complex systems and make them manageable.
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FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
The Architectural year book, University of Illinois. 4 [PDF]
, 1911 None issued 1918-1920 inclusive.Published -1917 by the Architectural Club; 1921- by the Architectural ...
core +1 more source
TowardsWeaving Software Architecture Models [PDF]
Fourth Workshop on Model-Based Development of Computer-Based Systems and Third International Workshop on Model-Based Methodologies for Pervasive and Embedded Software (MBD-MOMPES'06), 2006 Increasingly, UML metamodels and profiles are adopted to specify software architectures from different angles in order to cope with analysis specific modeling needs. In particular, whenever two or more analysis techniques are required over the same architectural model, different modeling tools and notations are required, and feedback from one model to ...
DI RUSCIO, DAVIDE +3 more
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Model-Driven Autonomic Architecture
Fourth International Conference on Autonomic Computing (ICAC'07), 2007 We present a generic architecture for developing fully-fledged autonomic systems out of non-autonomic components, and investigate how the architecture can be implemented using existing technologies. The universal policy engine at the core of the architecture is configured by means of a model of the resources placed under its control, and uses a set of ...
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