Results 121 to 130 of about 25,746,526 (333)
Modeling Architectural Pattern Variants
, 2010 Systematic modeling of architectural patterns is a challenging task mostly because of the inherent pattern variability and because pattern elements do not match the architectural abstractions of modeling languages.
Zdun, Uwe +2 more
core
Modeling the early stages of a user-centered process in architectural design through adaptation of the methodologies of New Product Design [PDF]
, 2009 In order to reach a degree of quality in architectural buildings that is likely to lead to user satisfaction, architectural design relies on integrating user-related information even before generation of building concepts.
BOUCHARD, Carole +2 more
core
Pattern-based customisable transformations for style-based service architecture evolution [PDF]
, 2010 Service-based architecture have now become commonplace, creating the need to address their systematic maintenance and evolution. We propose a layered patternbased transformation framework to support a stepwise and incremental Service-Oriented ...
Ahmad, Aakash +5 more
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
On Visual Computing for Architectural Heritage
, 2015 Aim of the chapter is to present a critical discourse on the use of visual computing for the study of historic architecture. From the analysis of the experiences of other scientific fields and of current researches in the architectural one, the paper ...
Stefano Brusaporci, BRUSAPORCI, STEFANO
core +1 more source
HeritageNeural radiance fields have emerged as a dominant paradigm for creating complex 3D environments incorporating synthetic novel views. However, 3D object removal applications utilizing neural radiance fields have lagged behind in effectiveness ...
Alexander Rusnak +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
BuildingsRapid urbanization across hot arid environments transforms local microclimates, yet linkages between density, layout, and outdoor thermal comfort remain inadequately characterized.
Alaa Eddine Bacha +9 more
doaj +1 more source