Results 111 to 120 of about 3,389,711 (296)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

A Study on the Visual Perception of Cultural Value Characteristics of Traditional Southern Fujian Architecture Based on Eye Tracking

open access: yesBuildings
The traditional Southern Fujian architecture serves as a reflection of the region’s deeply rooted cultural values. However, research on the architectural and cultural heritage of Southern Fujian remains scarce.
Jianxun Deng, Junlong Chen, Ying Lei
doaj   +1 more source

Enterprise and process architecture patterns

open access: yesBusiness Process Management Journal, 2011
PurposeThe purpose of this paper is to propose a method to support business process architecture and business process design, and present an application to the domain of public hospitals in Chile.Design/methodology/approachThis method is based on the formalization of generic architectures and their internal process structure, proposed in this work as ...
Oscar Barros, Cristian Julio
openaire   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Entropy as a Lens: Exploring Visual Behavior Patterns in Architects

open access: yesJournal of Eye Movement Research
This study examines how architectural expertise shapes visual perception, extending the “Seeing for Speaking” hypothesis into a non-linguistic domain. Specifically, it investigates whether architectural training influences unconscious visual processing ...
Renate Delucchi Danhier   +3 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Architectural Criticism between Public Debate and Autonomous Discipline (6)

open access: yes, 2016
Mobilizing the Nation via Architectural Criticism : The Architectural Review “Outrage” and “Counterattack” Erdem Erten Associate Professor, Izmir Institute of Technology, Department of Architecture In June 1955, The Architectural Review’s special issue ...
Mapping Architectural Criticism
core   +1 more source

Concepts in Architectural Patterns of Rural Housing (Case Study: the Villages of Ra`zavi Khorasan) [PDF]

open access: yesمسکن و محیط روستا, 2016
Concepts are the context of human thinking and acting and involve all aspects of his life. Like all man-constructions, architecture depends to the conceptual system of his mind.
Farhang Mozaffar   +2 more
doaj  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Design Pattern Prediction From Source Code Using LLM–Based Feature Engineering and SVM Classification

open access: yesIET Software
Typical source code (SC) metrics are useful in identifying and predicting the used design patterns in typical Java and Kotlin projects. However, typical SC metrics–based prediction tends to be less accurate.
Sirojiddin Komolov   +2 more
doaj   +1 more source

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