Results 1 to 10 of about 387,341 (70)

Adolescents with disabilities and caregivers experience of COVID-19 in rural Nepal

Frontiers in Public Health, 2023
IntroductionIntersecting vulnerabilities of disability, low socio-economic status, marginalization, and age indicate that adolescents with disabilities in low-and middle-income countries were uniquely affected by the COVID-19 pandemic.
Joanna Morrison, Niraj Poudyal, Insha Pun, Sagar Prasai, Nir Shrestha, Dipesh Khadka, Sushmita Shrestha, Brigitte Rohwerder, Mary Wickenden   +8 more
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Antigen footprint governs activation of the B cell receptor

Nature Communications, 2023
The antigen-B-cell-receptor interaction is the driving force of terminal B cell development that spans from B cell activation to antibody secreting plasma cells.
Alexey Ferapontov, Marjan Omer, Isabelle Baudrexel, Jesper Sejrup Nielsen, Daniel Miotto Dupont, Kristian Juul-Madsen, Philipp Steen, Alexandra S. Eklund, Steffen Thiel, Thomas Vorup-Jensen, Ralf Jungmann, Jørgen Kjems, Søren Egedal Degn   +12 more
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Describing adolescents with disabilities’ experiences of COVID-19 and other humanitarian emergencies in low- and middle-income countries: a scoping review

Global Health Action, 2022
Background The COVID-19 pandemic and other humanitarian emergencies exacerbate pre-existing inequalities faced by people with disabilities. They experience worse access to health, education, and social services, and increased violence in comparison with ...
Brigitte Rohwerder, Sara Wong, Shraddha Pokharel, Dipesh Khadka, Niraj Poudyal, Sagar Prasai, Nir Shrestha, Mary Wickenden, Joanna Morrison   +8 more
doaj   +1 more source

Application of Entropy Method to Quantify Future Ecological Flow in the Yellow River Basin

Entropy, 2021
Due to both anthropogenic and climate change impacts, precipitation and runoff in the Yellow River basin have decreased in the past 50 years, leading to more pressure in sustaining human beings and ecosystem needs.
Xinru Wang, Huijuan Cui
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GCN5 participates in KLF4-VEGFA feedback to promote endometrial angiogenesis

iScience, 2022
Summary: Endometrial angiogenesis is necessary for good endometrial receptivity. Krüppel-like factor 4 (KLF4) is a transcription factor that is essential for regulating angiogenesis.
Can Cao, Yuling Zhou, Yu Zhang, Yucong Ma, Shujin Du, Lijie Fan, Ruobing Niu, Yingmei Zhang, Ming He   +8 more
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Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats

Pharmaceutical Biology, 2022
Context Yiqi Huoxue Tongluo recipe (YHTR) is a traditional Chinese medicine for the treatment of chronic kidney disease, but its exact mechanism is not clear.Objectives To monitor the potential improvement of renal mitochondrial function in unilateral ...
Zhen He, Mengjuan Zhang, Hepeng Xu, Wenping Zhou, Chang Xu, Zheng Wang, Ming He, Xiangting Wang   +7 more
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Impact of the End Stage Renal Disease Prospective Payment System on the Use of Peritoneal Dialysis

Kidney International Reports, 2017
The End Stage Renal Disease (ESRD) Prospective Payment System (PPS), implemented by the Centers for Medicare and Medicaid Services in January 2011, encouraged use of peritoneal dialysis (PD) through various financial incentives. Our goal was to determine
Qian Zhang, Mae Thamer, Onkar Kshirsagar, Yi Zhang   +3 more
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Eplerenone Attenuates Fibrosis in the Contralateral Kidney of UUO Rats by Preventing Macrophage-to-Myofibroblast Transition

Frontiers in Pharmacology, 2021
Severe renal fibrosis often occurs in obstructive kidney disease, not only in the obstructed kidney but also in the contralateral kidney, causing renal dysfunction.
Yunzhao Xiong, Yunzhao Xiong, Yunzhao Xiong, Yi Chang, Yi Chang, Juan Hao, Juan Hao, Cuijuan Zhang, Cuijuan Zhang, Fan Yang, Fan Yang, Zheng Wang, Zheng Wang, Yunmeng Liu, Xiangting Wang, Xiangting Wang, Shengyu Mu, Qingyou Xu, Qingyou Xu, Qingyou Xu   +19 more
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Effects of Bushen-Tiaojing-Fang on the pregnancy outcomes of infertile patients with repeated controlled ovarian stimulation

Scientific Reports, 2021
Bushen-Tiaojing-Fang (BSTJF) is commonly used to treat infertility. This study investigated the effects of BSTJF on the pregnancy outcomes of patients with repeated controlled ovarian stimulation (COS), on mitochondrial function, and on oxidative stress ...
Yu-Cong Ma, Gui-Min Hao, Zhi-Ming Zhao, Na Cui, Yan-Li Fan, Shuan-Cheng Zhang, Jing-Wei Chen, Yu-Cong Cao, Feng-Li Guan, Jing-Ran Geng, Bu-Lang Gao, Hui-Lan Du   +11 more
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Esaxerenone inhibits the macrophage-to-myofibroblast transition through mineralocorticoid receptor/TGF-β1 pathway in mice induced with aldosterone

Frontiers in Immunology, 2022
Renal fibrosis is the inevitable pathway of the progression of chronic kidney disease to end-stage renal disease, which manifests as progressive glomerulosclerosis and renal interstitial fibrosis.
Panpan Qiang, Panpan Qiang, Juan Hao, Juan Hao, Fan Yang, Fan Yang, Yutong Han, Yutong Han, Yi Chang, Yi Chang, Yunqian Xian, Yunqian Xian, Yunzhao Xiong, Yunzhao Xiong, Xiaomeng Gao, Xiaomeng Gao, Lijuan Liang, Tatsuo Shimosawa, Qingyou Xu, Qingyou Xu, Qingyou Xu   +20 more
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