Results 131 to 140 of about 59,821 (310)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

The Transformation Of Conception Of Architecture In Architectural Practice

open access: yes, 2014
Tez (Yüksek Lisans) -- İstanbul Teknik Üniversitesi, Fen Bilimleri Enstitüsü, 2013Thesis (M.Sc.) -- İstanbul Technical University, Institute of Science and Technology, 2013Tez çalışmasının başlangıcında, sorular sorarak çıkış noktası aranmıştır ...
Pektaş, Aslı Nur
core  

A Bourdieusian Lens onto Professions, A Case Study of Architecture [PDF]

open access: yes, 2013
This study explores the potential of Bourdieu’s sociology for re-orienting the sociology of professions. Despite differences in methodology and theoretical priorities, neither classical theories nor the contemporary studies completely break with the view
Sahin-Dikmen, Melahat
core  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Architecture and ethnography : preliminary reflections on the structure and organization of architectural practice

open access: yes, 2016
This paper explores crossovers between architectural practice and ethnography, with an emphasis on management structures and their relationship to organisational models.
Askland, Hedda H.   +3 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Practicing Reform: Experiments in Post-Revolutionary Chinese Architectural Production, 1973-1989

open access: yes, 2015
This article explores the relationship between architectural praxis and political economic reform in China between 1973 and 1989. It looks specifically at how modifications in the practice of architectural design corresponded to the project of China’s ...
Roskam, C
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

Concinnitas in the architectural theory and practice of Leon Battista Alberti.

open access: yes, 1985
In his treatise on architecture, de re aedificatoria, Leon Battista Alberti (1404 - 72) described Beauty in architecture as concinnitas: a harmony or congruity of the various parts of a building assembled according to principles :summarised by three ...
Tavernor, R.W
core   +1 more source

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