Results 121 to 130 of about 59,821 (310)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Implementing Bioclimatic Design in Sustainable Architectural Practice

open access: yes
Today one of the topical issues in Latvia relates to the compliance of the architectural practice with the modern concept of sustainable development.
Bondars, Edgars
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Architectural design principles and processes for sustainability : towards a typology of sustainable building design

open access: yes, 2011
The shift towards sustainable buildings requires a transformation of the architectural design process. This paper examines how sustainability is embedded into design methodology and mapped onto, or has transformed, the design process in practise ...
Grierson, David, Moultrie, Carolyn Mary
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Journal of Architectural Research and Development

open access: yes, 2018
Journal of Architectural Research and Development is an international peer-reviewed and open access journal which is devoted to establish a bridge between theory and practice in the fields of architectural and design research, urban planning and built ...
Alessandra Capanna
core  

Situated Design-Thinking in Architectural Practice:

open access: yesArdeth, 2018
Nearly thirty-five years ago Donald Schön proposed an epistemology of design practice as an antidote to the crisis of legitimacy in architecture and other professional design disciplines.
Laura Malinin
doaj  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

A Historical and Critical Assessment of Parametricism as an Architectural Style in the 21st Century

open access: yesBuildings
Architectural styles have evolved, with distinct periods marked by unique styles that reflect broader artistic movements. Despite extensive research on traditional and contemporary architectural styles, there remains a gap in understanding the ...
Ameen Mokhles Youns, Kokan Grchev
doaj   +1 more source

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