Results 101 to 110 of about 59,821 (310)

Beyond Buildings: The Evolving Architectural Problem

Architecture
Building on Gutman’s (1987) argument that architectural practice should reflect the nature of the problem, this article explores four eras of architectural practice: the Patronage Model, the Clientage Model, the Transitional Models, and Future Models ...
Keith Diaz Moore
doaj   +1 more source

A Practical Parallel Architecture for Stacks Filters

Journal of VLSI signal processing systems for signal, image and video technology, 2004
Stack filters belong to the class of non-linear filters and include the well-known median filter, weighted median filters, order statistic filters and weighted order statistic filters. Any stack filter can be implemented by using the parallel threshold decomposition architecture which allows implementing their non-linear processing by means of a ...
Maria J. Avedillo, José M. Quintana, Hamid El Alami, Antonio Jiménez-Calderón   +3 more
openaire   +2 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Practices of stigmergy in architectural work

Proceedings of the 2007 international ACM conference on Conference on supporting group work - GROUP '07, 2007
Actors coordinate their cooperative efforts by acting on the evidence of work previously accomplished. The paper introduces, on the basis of a field study, the concept of stigmergy to the analysis of coordinative practices in architectural work. It distinguishes between practices of stigmergy and articulation work.
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Architectural students' year-out training experience in architectal offices in the UK

, 2015
This paper investigates architectural students’ ‘year-out’ learning experiences in architectural offices after completing RIBA Part I study within a UK university.
Orr, Kevin, Gao, Yun
core  

Social responsibility for architects in a global construction practice

PlaNext, 2018
This article seeks to conceptualise an understanding of the role and the nature of socially responsible architects and their architectural firms in a rapidly growing global construction market.
Clarissa Rhomberg
doaj  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Problem based learning in architectural education

, 2007
There is limited published research and discussion on pedagogical approaches in architectural education. Problem (or Project) Based Learning is used successfully in other professional disciplines, and, consequently, there have been attempts to utilise ...
Bridges, Alan
core