Results 51 to 60 of about 1,445,677 (303)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
THE COMPARISON BETWEEN NMF AND ICA IN PIGMENT MIXTURE IDENTIFICATION OF ANCIENT CHINESE PAINTINGS [PDF]
Since the colour in painting cultural relics observed by our naked eyes or hyperspectral cameras is usually a mixture of several kinds of pigments, the mixed pigments analysis will be an important subject in the field of ancient painting conservation and
Y. Liu +7 more
doaj +1 more source
The reconstruction of drawn architecture
Among the many cases concerning the process of digital hypothetical 3D reconstruction a particular case is constituted by never realized projects and plans. They constitute projects designed and remained on paper that, albeit documented by technical drawings, they pose the typical problems that are common to all other cases.
Fabrizio Ivan Apollonio +4 more
openaire +4 more sources
Reconstructing the architecture of the ancestral amniote genome [PDF]
Abstract Motivation: The ancestor of birds and mammals lived approximately 300 million years ago. Inferring its genome organization is key to understanding the differentiated evolution of these two lineages. However, detecting traces of its chromosomal organization in its extant descendants is difficult due to the accumulation of ...
Ouangraoua, Aïda +2 more
openaire +4 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The changing patterns of architectural design education [PDF]
Digital technologies have been introduced to students of architecture for over two decades and at present it could be argued that students are producing some of the highest quality designs, and some of the most interesting forms ever to come from ...
Horne, Margaret, Giddings, Bob
core
THE ONE TO MULTIPLE AUTOMATIC HIGH ACCURACY REGISTRATION OF TERRESTRIAL LIDAR AND OPTICAL IMAGES [PDF]
The registration of ground laser point cloud and close-range image is the key content of high-precision 3D reconstruction of cultural relic object. In view of the requirement of high texture resolution in the field of cultural relic at present, The ...
Y. Wang +11 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
This article raises questions about the need for a balanced and comprehensive approach to the conservation of Lisbon's historic centre, Baixa Pombalina.
Ivanova Svetlana Yu., Tarasova Irina V.
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

