Results 61 to 70 of about 17,548 (317)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Survey data on digitalization of building procurement process by architectural firms in Abuja, Nigeria

open access: yesData in Brief, 2018
This data article describes the dataset on the digital technologies and applications used by architectural firms in the delivery of building projects. The data set was sourced through a questionnaire survey of 75 registered architectural firms in Abuja ...
Eziyi O. Ibem   +4 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Spatially integrative metrics reveal hidden vulnerability of microtidal salt marshes

open access: yesNature Communications, 2017
Point measurements have historically been used to assess salt marsh vulnerability; however, these metrics do not integrate over the necessary spatiotemporal scales.
Neil K. Ganju   +5 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Graphic Studies on the Built Heritage, a Critical Review. Technical Advances VS Traditional Studies

open access: yesimg journal
Research on the built heritage should periodically review the good practices to be used in surveying theories and practices. Written and graphic precedents provide a valuable knowledge of historical buildings built over centuries.
Pilar Chìas Navarro
doaj   +1 more source

Software Architecture Styles: A Survey [PDF]

open access: yesInternational Journal of Computer Applications, 2014
This research deals with an important issue in software development. It is concerned with software development with the help of software architecture styles. Software industry uses many architecture styles namely, pipe and filter, object oriented, event invocation, process control layered, data centered architecture etc.
openaire   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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